公开(公告)号：US08901163B2

公开(公告)日：2014-12-02

申请号：US11648941

申请日：2007-01-03

申请人： Jeffrey D. Parks ,  L. Dean Parks

发明人： Jeffrey D. Parks ,  L. Dean Parks

IPC分类号： A61K31/366 ,  A61P17/00

CPC分类号： A61K31/7048 ,  A61K9/0014 ,  A61K31/366

摘要： A method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by an insect or arthropod sting or bite, or a skin contact with a noxious weed or plant is disclosed. The method includes topically applying a dermatological composition containing an avermectin compound to an affected area immediately after said sting or bite, or said skin contact occurs. The method further includes moistening the affected area first prior to application of the dermatological composition.

摘要翻译： 公开了一种治疗由昆虫或节肢动物刺痛或咬伤引起的感觉异常，染色和瘙痒，或与有害杂草或植物的皮肤接触的方法。 该方法包括在所述刺痛或咬伤之后立即将含有阿维菌素化合物的皮肤病学组合物局部施用于受影响的区域，或所述皮肤接触发生。 该方法还包括在施用皮肤病学组合物之前首先润湿受影响的区域。

公开(公告)号：US20130178434A1

公开(公告)日：2013-07-11

申请号：US13823330

申请日：2011-10-14

申请人： L. Dean Parks ,  Jeffrey D. Parks

发明人： L. Dean Parks ,  Jeffrey D. Parks

IPC分类号： A61K31/7048 ,  A61K31/365

CPC分类号： A61K31/7048 ,  A61K9/0046 ,  A61K9/06 ,  A61K31/365 ,  A61K47/10 ,  A61K47/14 ,  A61K47/26

摘要： A method of treating otitis externa is disclosed. The method includes topically applying an otic composition containing an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds or milbemycin compounds and a pharmaceutically acceptable carrier into the external auditory canal and the auricle of an affected ear of an individual suffering from otitis externa.

摘要翻译： 公开了一种治疗外耳炎的方法。 该方法包括将包含有效量的一种或多种大环内酯化合物（包括除虫菌素化合物或米尔倍霉素化合物）和药学上可接受的载体局部施用于外耳道和患有外耳炎的个体的受影响的耳朵的耳廓 。

公开(公告)号：US06433006B1

公开(公告)日：2002-08-13

申请号：US09976914

申请日：2001-10-12

申请人： L. Dean Parks

发明人： L. Dean Parks

IPC分类号： A61K3135

摘要： A method of treatment of seborrheic dermatitis includes the application, in the form of either a lotion or a cream, of a mixture including a therapeutically effective amount of ivermectin in water preferably in a concentration of about 750 micrograms per milliliter (mcg/ml), in the case of a lotion, and with a pharmaceutically acceptable carrier if used as a cream. Such a lotion or cream is applied nightly preferably for a period of seven days and then employed on a maintenance basis one to four times per month.

公开(公告)号：US20130178433A1

公开(公告)日：2013-07-11

申请号：US13823226

申请日：2011-10-14

申请人： L. Dean Parks ,  Jeffrey D. Parks

发明人： L. Dean Parks ,  Jeffrey D. Parks

IPC分类号： A61K31/7048 ,  A61K31/365

CPC分类号： A61K31/7048 ,  A61K9/0031 ,  A61K9/06 ,  A61K31/365

摘要： A method of treating hemorrhoids is disclosed. The method includes locally administering a composition including an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds, milbemycin compounds, or mixture thereof and a pharmaceutically acceptable carrier to the affected anorectal region of an individual suffering from hemorrhoid.

摘要翻译： 公开了治疗痔疮的方法。 该方法包括将有效量的一种或多种大环内酯化合物，包括阿维菌素化合物，米尔倍霉素化合物或其混合物和药学上可接受的载体局部施用于患有痔疮的个体的受影响的肛门直肠区域的组合物。

公开(公告)号：US20130172282A1

公开(公告)日：2013-07-04

申请号：US13823387

申请日：2011-10-14

申请人： L. Dean Parks ,  Jeffrey D. Parks

发明人： L. Dean Parks ,  Jeffrey D. Parks

IPC分类号： A61K31/7048 ,  A61K31/365

CPC分类号： A61K31/7048 ,  A61K31/35 ,  A61K31/365

摘要： A method of treating herpes simplex virus infection or varicella zoster virus infection is disclosed. The method includes topically applying a composition containing an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds or milbemycin compounds and a pharmaceutically acceptable carrier to the affected area of an individual suffering from herpes simplex virus infection or varicella zoster virus infection.

摘要翻译： 公开了治疗单纯疱疹病毒感染或水痘带状疱疹病毒感染的方法。 该方法包括将有效量的一种或多种大环内酯化合物，包括阿维菌素化合物或米尔倍霉素化合物和药学上可接受的载体局部施用于患有单纯疱疹病毒感染或水痘带状疱疹病毒感染的个体的受影响区域。

公开(公告)号：US06399652B1

公开(公告)日：2002-06-04

申请号：US09988914

申请日：2001-11-19

申请人： L. Dean Parks

发明人： L. Dean Parks

IPC分类号： A61K3135

CPC分类号： A61Q19/10 ,  A61K8/498 ,  A61K31/35 ,  A61K31/704 ,  A61Q19/00 ,  Y10S514/859

摘要： Methods for treating acne vulgaris are disclosed. The treatment includes topical application of a dermatological composition containing an avermectin compound to the affected areas of a patient alone, or in conjunction with other conventional methods of treating acne vulgaris. The dermatological composition contains an avermectin compound in a pharmaceutically acceptable carrier, including water, glycols, alcohols, lotions, creams, gels, emulsions, sprays, soaps, body washes, facial cleansers, and facial masks.

公开(公告)号：US07071228B2

公开(公告)日：2006-07-04

申请号：US10278706

申请日：2002-10-23

申请人： L. Dean Parks

发明人： L. Dean Parks

IPC分类号： A01N37/00 ,  A61K31/19

CPC分类号： A61K31/203 ,  Y10S514/859

摘要： A method of treating said musculoskeletal and connective tissue inflammations including osteoarthritis and associated articular and periarticular inflammations, and non-articular Rheumatism including capsulitis, tendonitis, fibrositis, and perarticular inflammations is disclosed. The method includes administering to a patient of a therapeutically effective amount of a composition comprising 13-cis-retinoic acid. Preferably, the treatment method includes administering to a patient of an initial dosage of a composition comprising 13-cis-retinoic acid for an initial treatment period, and thereafter administering a maintenance dosage of the composition.

摘要翻译： 公开了一种治疗所述肌肉骨骼和结缔组织炎症的方法，包括骨关节炎和相关关节和关节周围炎症，以及非关节风湿病，包括囊膜炎，腱炎，纤维性炎症和关节炎。 该方法包括向患者施用治疗有效量的包含13-顺 - 视黄酸的组合物。 优选地，治疗方法包括在初始治疗期间向患者施用包含13-顺 - 视黄酸的组合物的初始剂量，然后施用组合物的维持剂量。

公开(公告)号：US06399651B1

公开(公告)日：2002-06-04

申请号：US09976915

申请日：2001-10-12

申请人： L. Dean Parks

发明人： L. Dean Parks

IPC分类号： A61K3135

CPC分类号： A61K8/498 ,  A61K31/35 ,  A61K31/704 ,  A61Q19/00 ,  Y10S514/859

摘要： A method for treating dermatoses including transient acantholytic dermatitis, acne miliaris necrotica, acne varioliformis, perioral dermatitis, and acneiform eruptions is disclosed. The method includes topical application of a dermatological composition containing an avermectin compound to the affected areas of a patient.

公开(公告)号：US08912151B2

公开(公告)日：2014-12-16

申请号：US13823226

申请日：2011-10-14

申请人： L. Dean Parks ,  Jeffrey D. Parks

发明人： L. Dean Parks ,  Jeffrey D. Parks

IPC分类号： A61K31/70 ,  A61K31/7048 ,  A61K31/365 ,  A61K9/00 ,  A61K9/06

CPC分类号： A61K31/7048 ,  A61K9/0031 ,  A61K9/06 ,  A61K31/365

摘要： A method of treating hemorrhoids is disclosed. The method includes locally administering a composition including an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds, milbemycin compounds, or mixture thereof and a pharmaceutically acceptable carrier to the affected anorectal region of an individual suffering from hemorrhoid.

摘要翻译： 公开了治疗痔疮的方法。 该方法包括将有效量的一种或多种大环内酯化合物，包括阿维菌素化合物，米尔倍霉素化合物或其混合物和药学上可接受的载体局部施用于患有痔疮的个体的受影响的肛门直肠区域的组合物。

公开(公告)号：US08901091B2

公开(公告)日：2014-12-02

申请号：US13823387

申请日：2011-10-14

申请人： L. Dean Parks ,  Jeffrey D. Parks

发明人： L. Dean Parks ,  Jeffrey D. Parks

IPC分类号： A61K31/70 ,  A61K31/7048 ,  A61K31/35 ,  A61K31/365

CPC分类号： A61K31/7048 ,  A61K31/35 ,  A61K31/365

摘要： A method of treating herpes simplex virus infection or varicella zoster virus infection is disclosed. The method includes topically applying a composition containing an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds or milbemycin compounds and a pharmaceutically acceptable carrier to the affected area of an individual suffering from herpes simplex virus infection or varicella zoster virus infection.

摘要翻译： 公开了治疗单纯疱疹病毒感染或水痘带状疱疹病毒感染的方法。 该方法包括将有效量的一种或多种大环内酯化合物，包括阿维菌素化合物或米尔倍霉素化合物和药学上可接受的载体局部施用于患有单纯疱疹病毒感染或水痘带状疱疹病毒感染的个体的受影响区域。