公开(公告)号：US06361765B1

公开(公告)日：2002-03-26

申请号：US09586589

申请日：2000-06-02

申请人： Bruce Steven Emslie ,  Laura Dimitrova Stoimenof ,  Graham Andrew Turner

发明人： Bruce Steven Emslie ,  Laura Dimitrova Stoimenof ,  Graham Andrew Turner

IPC分类号： A61K732

CPC分类号： A61Q15/00 ,  A61K8/37

摘要： Antiperspirant compositions herein comprise an antiperspirant active, together with a carrier and a structurant for the carrier which comprises an organic wax having a melting point of from 40 to 90° C. of which at least 60% of the weight of the wax is provided by at least one aliphatic ester satisfying the formula: CH3—(CH2)n—CO—(CH2)m—CH3 in which n is from 9 to 39 and m is from 0 to 35 to form a solid or a soft solid. The compositions can be anhydrous, in the form of a suspension of antiperspirant active, or can comprise aqueous emulsions. The formulations structured by the selected waxes provide lower visible deposits on topical application compared with conventional wax-structured formulations and the waxes are effective at structuring/thickening at a proportion below that in conventional wax-structured formulations. It is especially desirable to employ emulsion formulations comprising a continuous phase which comprises from 10 to 35% volatile silicone oil, and from 5 to 15% non-volatile hydrophobic oil, from 40 to 75% of ta disperse aqueous phase which contains from 1 to 35% of an antiperspirant or deodorant active, from 7 to 25% of a wax structurant, from 0.1 to 10% of an emulsifier, and preferably contains up to 5% insoluble particulate materials, % s being by weight based on the composition.

摘要翻译： 本发明的止汗剂组合物包含止汗剂活性物，以及载体和用于载体的结构剂，其包含熔点为40至90℃的有机蜡，其中至少60重量％的蜡由 至少一种满足下式的脂肪族酯：其中n为9〜39，m为0〜35，形成固体或软固体。 组合物可以是无水的，以止汗活性物的悬浮液形式，或者可以包含水性乳液。由常规蜡结构制剂相比，由所选择的蜡构成的制剂在局部施用上提供较低的可见沉积物，并且该蜡在结构上是有效的 /增稠比例低于常规蜡结构制剂中的比例。特别希望使用包含连续相的乳液制剂，其包含10至35％的挥发性硅油和5至15％的非挥发性疏水性油，来自 40至75％的分散水相，其含有1至35％的止汗剂或除臭剂活性剂，7至25％的蜡结构剂，0.1至10％的乳化剂，并且优选含有至多5％的不溶性 颗粒物质，％s以组合物为基准。