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公开(公告)号:US20130309173A2
公开(公告)日:2013-11-21
申请号:US13501077
申请日:2010-10-08
申请人: Tina Wong , Li-Fong Seet
发明人: Tina Wong , Li-Fong Seet
IPC分类号: A61K31/713 , A61K33/00 , A61K39/395 , A61K49/00 , C07H21/02 , A61P27/06 , A61K9/48 , A61K9/00 , G01N33/573 , C12Q1/02 , A61P27/02 , A61K38/02 , A61K9/127
CPC分类号: A61K31/7105 , A61K38/00 , A61K49/0008 , C12N15/113 , C12N2310/14 , G01N33/5088
摘要: The present invention relates to methods and compositions for the modulation of wound healing and/or the production of extracellular membrane components by modulating the activity and/or amount of secreted protein acidic and rich in cysteine (SPARC) protein. The invention further provides methods for identifying compounds useful in the above-mentioned methods and compositions.
摘要翻译: 本发明涉及通过调节酸性和富含半胱氨酸(SPARC)蛋白质的分泌蛋白质的活性和/或量来调节伤口愈合和/或产生细胞外膜组分的方法和组合物。 本发明还提供用于鉴定可用于上述方法和组合物的化合物的方法。
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公开(公告)号:US20130064774A2
公开(公告)日:2013-03-14
申请号:US13501077
申请日:2010-10-08
申请人: Tina Wong , Li-Fong Seet
发明人: Tina Wong , Li-Fong Seet
IPC分类号: A61K31/713 , A61K33/00 , A61K39/395 , A61K49/00 , C07H21/02 , A61P27/06 , A61K9/48 , A61K9/00 , G01N33/573 , C12Q1/02 , A61P27/02 , A61K38/02 , A61K9/127
CPC分类号: A61K31/7105 , A61K38/00 , A61K49/0008 , C12N15/113 , C12N2310/14 , G01N33/5088
摘要: The present invention relates to methods and compositions for the modulation of wound healing and/or the production of extracellular membrane components by modulating the activity and/or amount of secreted protein acidic and rich in cysteine (SPARC) protein. The invention further provides methods for identifying compounds useful in the above-mentioned methods and compositions.
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公开(公告)号:US20120244077A1
公开(公告)日:2012-09-27
申请号:US13501077
申请日:2010-10-08
申请人: Tina Wong , Li-Fong Seet
发明人: Tina Wong , Li-Fong Seet
IPC分类号: A61K31/713 , A61K33/00 , A61K39/395 , A61K49/00 , C07H21/02 , A61P27/06 , A61K9/48 , A61K9/00 , G01N33/573 , C12Q1/02 , A61P27/02 , A61K38/02 , A61K9/127
CPC分类号: A61K31/7105 , A61K38/00 , A61K49/0008 , C12N15/113 , C12N2310/14 , G01N33/5088
摘要: The present invention relates to methods and compositions for the modulation of wound healing and/or the production of extracellular membrane components by modulating the activity and/or amount of secreted protein acidic and rich in cysteine (SPARC) protein. The invention further provides methods for identifying compounds useful in the above-mentioned methods and compositions.
摘要翻译: 本发明涉及通过调节酸性和富含半胱氨酸(SPARC)蛋白质的分泌蛋白质的活性和/或量来调节伤口愈合和/或产生细胞外膜组分的方法和组合物。 本发明还提供用于鉴定可用于上述方法和组合物的化合物的方法。
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