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公开(公告)号：US08900629B2
公开(公告)日：2014-12-02
申请号：US13335067
申请日：2011-12-22
CPC分类号： A61K9/0056 , A61K9/4816 , A61K47/36
摘要： The present disclosure provides rapidly dissolving oral capsules and films comprising pullulan, a plasticizer, and a dissolution enhancing agent.
摘要翻译： 本发明提供快速溶解的口服胶囊和包含支链淀粉，增塑剂和溶解增强剂的薄膜。
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公开(公告)号：US07235258B1
公开(公告)日：2007-06-26
申请号：US09691237
申请日：2000-10-19
CPC分类号： A61K9/2866 , A61K9/286 , A61K9/2886 , A61K9/5042 , A61K9/5047 , A61K9/5073
摘要： Sustained-release compositions for delivering therapeutic concentrations of isovaleramide, isovaleric acid, and certain structurally related compounds are provided for the treatment for a variety of pathological conditions, including epilepsy and spasticity, which are ameliorated by effecting a modulation of CNS activity. The ability of the compositions to sustain relatively constant levels of the drug at a therapeutic dose in the serum for extended periods of time enables a once or twice daily administration schedule.
摘要翻译： 提供用于递送治疗浓度的异戊酰胺，异戊酸和某些结构相关化合物的缓释组合物用于治疗多种病理状况，包括通过进行CNS活性调节来改善癫痫和痉挛状态。 组合物在血清中以更长时间段的治疗剂量维持相对恒定水平的药物的能力使得能够每天一次或两次给药。
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公开(公告)号：US20130005831A1
公开(公告)日：2013-01-03
申请号：US13335067
申请日：2011-12-22
CPC分类号： A61K9/0056 , A61K9/4816 , A61K47/36
摘要： The present disclosure provides rapidly dissolving oral capsules and films comprising pullulan, a plasticizer, and a dissolution enhancing agent.
摘要翻译： 本发明提供快速溶解的口服胶囊和包含支链淀粉，增塑剂和溶解增强剂的薄膜。
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