公开(公告)号：US08975414B2

公开(公告)日：2015-03-10

申请号：US13606640

申请日：2012-09-07

Applicant: Linda A. Kunz ,  Steven A. Cohen

Inventor： Linda A. Kunz ,  Steven A. Cohen

IPC: C07F15/00

CPC classification number: C07F15/0053 ,  C07F15/0046

Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru═CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3 and/or two of R1, R2, and R3 taken together may optionally form a ring with phosphorous.

Abstract translation: 制备钌卡宾络合物前体的方法包括使钌精炼盐与卤化氢反应形成钌中间体，并使钌中间体与L型配体反应以形成钌卡宾复合物前体。 制备钌乙烯基卡巴复合物的方法包括将钌卡宾络合物前体转化为卤化钌卤化物络合物，并使卤化钌卤化物络合物与炔丙基卤反应形成钌乙烯基卡巴复合物。 制备钌卡宾络合物的方法包括将钌卡宾络合物前体转化成具有结构（PR1R2R3）2Cl2Ru=CH-R4的钌卡宾络合物，其中R 1，R 2，R 3和R 4相同或不同，并且其中共价键 可以任选地存在于R 1，R 2和R 3中的两个或多个之间，和/或R 1，R 2和R 3中的两个可以任选地与磷形成环。

公开(公告)号：US08779152B2

公开(公告)日：2014-07-15

申请号：US13272788

申请日：2011-10-13

Applicant: Linda A. Kunz ,  Steven A. Cohen ,  Melvin L. Luetkens, Jr.

Inventor： Linda A. Kunz ,  Steven A. Cohen ,  Melvin L. Luetkens, Jr.

IPC: C07F15/00

CPC classification number: C07F15/0046 ,  B01J31/2295 ,  C07F15/0053

Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru═CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3.

Abstract translation: 制备钌卡宾络合物前体的方法包括使钌精炼盐与卤化氢反应形成钌中间体，并使钌中间体与L型配体反应以形成钌卡宾复合物前体。 制备钌乙烯基卡巴复合物的方法包括将钌卡宾络合物前体转化为卤化钌卤化物络合物，并使卤化钌卤化物络合物与炔丙基卤反应形成钌乙烯基卡巴复合物。 制备钌卡宾络合物的方法包括将钌卡宾络合物前体转化成具有结构（PR1R2R3）2Cl2Ru=CH-R4的钌卡宾络合物，其中R 1，R 2，R 3和R 4相同或不同，并且其中共价键 可以任选地存在于R 1，R 2和R 3中的两个或多个之间。

公开(公告)号：US20130096313A1

公开(公告)日：2013-04-18

申请号：US13272788

申请日：2011-10-13

Applicant: Linda A. Kunz ,  Steven A. Cohen ,  Melvin L. Luetkens, JR.

Inventor： Linda A. Kunz ,  Steven A. Cohen ,  Melvin L. Luetkens, JR.

IPC: C07F15/00

CPC classification number: C07F15/0046 ,  B01J31/2295 ,  C07F15/0053

Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru═CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3.

Abstract translation: 制备钌卡宾络合物前体的方法包括使钌精炼盐与卤化氢反应形成钌中间体，并使钌中间体与L型配体反应以形成钌卡宾复合物前体。 制备钌乙烯基卡巴复合物的方法包括将钌卡宾络合物前体转化为卤化钌卤化物络合物，并使卤化钌卤化物络合物与炔丙基卤反应形成钌乙烯基卡巴复合物。 制备钌卡宾络合物的方法包括将钌卡宾络合物前体转化成具有结构（PR1R2R3）2Cl2Ru = CH-R4的钌卡宾络合物，其中R1，R2，R3和R4是相同或不同的，其中共价键 可以任选地存在于R 1，R 2和R 3中的两个或多个之间。

公开(公告)号：US20130096314A1

公开(公告)日：2013-04-18

申请号：US13606640

申请日：2012-09-07

Applicant: Linda A. Kunz ,  Steven A. Cohen

Inventor： Linda A. Kunz ,  Steven A. Cohen

IPC: C07F19/00 ,  C07F15/00

CPC classification number: C07F15/0053 ,  C07F15/0046

Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru═CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3 and/or two of R1, R2, and R3 taken together may optionally form a ring with phosphorous.

Abstract translation: 制备钌卡宾络合物前体的方法包括使钌精炼盐与卤化氢反应形成钌中间体，并使钌中间体与L型配体反应以形成钌卡宾复合物前体。 制备钌乙烯基卡巴复合物的方法包括将钌卡宾络合物前体转化为卤化钌卤化物络合物，并使卤化钌卤化物络合物与炔丙基卤反应形成钌乙烯基卡巴复合物。 制备钌卡宾络合物的方法包括将钌卡宾络合物前体转化成具有结构（PR1R2R3）2Cl2Ru = CH-R4的钌卡宾络合物，其中R1，R2，R3和R4是相同或不同的，其中共价键 可以任选地存在于R 1，R 2和R 3中的两个或多个之间，和/或R 1，R 2和R 3中的两个可以任选地与磷形成环。