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公开(公告)号:US07384656B2
公开(公告)日:2008-06-10
申请号:US11351963
申请日:2006-02-10
申请人: Gopi R. Menon , David J. Fast , Lisa A. Rozga , Yumei Lin , David W. Krempin , John N. Goolsby
发明人: Gopi R. Menon , David J. Fast , Lisa A. Rozga , Yumei Lin , David W. Krempin , John N. Goolsby
CPC分类号: A61K31/015 , A61K31/192 , A61K31/704 , A61K36/28 , A61K36/53 , A61K36/535 , A61K36/59 , A61K36/736 , A61K36/906 , A61K2300/00
摘要: An composition and related method that prevents, inhibits and/or mitigates an allergic response by down regulating the production of IgE, down regulating the binding of IgE antibodies to receptors on cells, and/or inhibiting allergy mediators, for example, histamine, prostoglandin D2, or luekotriene C4 release. The composition comprises at least one of the following ingredients: luteolin from Perilla leaf or seed, Cinnamon, Kiwi, Picao preto, Hesperidin, Acerola cherry, Guaco, Holy Basil, Kakadu, Solamum, Rosmarinic acid, Tinospora and Aframomum. In one embodiment, the composition at least three different ingredients selected from Cinnamon, Acerola, Luteolin and Picao preto. Optionally, these ingredients can be combined with at least one of Aframomum, Rosmarinic acid, and Tinospora. The composition is administered with effective amounts to prevent, inhibit and/or mitigate allergic responses.
摘要翻译: 通过调节IgE的产生来抑制,抑制和/或减轻过敏反应的组合物和相关方法,可以减少IgE抗体与细胞上的受体的结合,和/或抑制过敏介质,例如组胺,前列腺素D 或二烯三醇C 4 N 3脱离物。 组合物包含以下成分中的至少一种:来自紫苏叶或种子的木犀草素,肉桂,猕猴桃,Picao preto,Hesperidin,Acerola cherry,Guaco,Holy Basil,Kakadu,Solamum,Rosmarinic acid,Tinospora和Aframomum。 在一个实施方案中,组合物至少三种不同的成分选自肉桂,Acerola,木犀草素和Picao preto。 任选地,这些成分可以与Aframomum,迷迭香酸和Tinospora中的至少一种组合。 施用有效量的组合物以预防,抑制和/或减轻过敏反应。