公开(公告)号：US07741019B2

公开(公告)日：2010-06-22

申请号：US10415222

申请日：2001-11-01

Applicant: Eleftherios P. Diamandis ,  Liu-Ying Luo

Inventor： Eleftherios P. Diamandis ,  Liu-Ying Luo

IPC: C12Q1/00 ,  G01N33/574

CPC classification number: G01N33/57449 ,  G01N2333/96455

Abstract: A method for the diagnosis, prognosis, and monitoring of ovarian cancer in a subject by detecting hK10 in a sample from the subject, preferably a serum sample or tumor tissue extract. hK10 may be measured using a reagent that detects or binds to hK10 preferably antibodies specifically reactive with hK10 or a part thereof. Imaging methods for tumors associated with hK10 are also described using an agent that binds to hK10 which had a label for imaging the tumor.

Abstract translation: 一种通过检测来自受试者的样品中的hK10，优选血清样品或肿瘤组织提取物来诊断，预后和监测受试者的卵巢癌的方法。 可以使用检测或结合hK10的试剂优选hK10，优选与hK10或其一部分特异性反应的抗体。 还使用与hK10结合的试剂描述与hK10相关的肿瘤的成像方法，所述试剂具有用于成像肿瘤的标记。