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1.发明授权Panel of micrornas that silence the MCL-1 gene and sensitize cancer cells to ABT-263 有权将微绒毛组织沉默MCL-1基因并使癌细胞对ABT-263敏感公开(公告)号：US08742083B1
公开(公告)日：2014-06-03
申请号：US12978086
申请日：2010-12-23
Applicant: Dimitri Semizarov , Xin Lu , Lloyd T. Lam
Inventor： Dimitri Semizarov , Xin Lu , Lloyd T. Lam
CPC classification number: C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , C12Q2600/178
Abstract: MicroRNAs (miRNAs) that sensitize cancer cells to Bcl-2 family protein inhibitors are identified and described. Oligonucleotide panels, arrays and methods using the sensitizing miRNAs are also disclosed.
Abstract translation: 鉴定并描述了使癌细胞对Bcl-2家族蛋白抑制剂敏感的微小RNA（miRNA）。 还公开了使用敏化miRNA的寡核苷酸片段，阵列和方法。
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