专利检索 ap:"Luyang WANG" 第 1 页

1.

发明申请
GO-GD-DTPA COMPLEX, PREPARATION METHOD THEREOF, AND MRI CONTRAST AGENT COMPRISING THE SAME 有权

公开(公告)号：US20130079503A1

公开(公告)日：2013-03-28

申请号：US13607961

申请日：2012-09-10

申请人： Hyo Young LEE , Luyang WANG

发明人： Hyo Young LEE , Luyang WANG

IPC分类号： C07F5/00

CPC分类号： C07F5/00 , A61K49/105 , C07D493/22 , C07F5/003

摘要： Disclosed herein is a GO-Gd-DTPA (gadolinum-diethylenetriamine pentaacetic-graphene oxide) complex, which is formed by an ester bond of graphene oxide (GO) and gadopentetic acid (Gd-DTPA). Since the GO-Gd-DTPA can stably exist in the body because it has high stability in water, it is expected that it can be effectively used as an MRI contrast agent.

2.

发明授权
GO-Gd-DTPA complex, preparation method thereof, and MRI contrast agent comprising the same 有权
标题翻译： GO-Gd-DTPA复合物及其制备方法和包含其的MRI造影剂

公开(公告)号：US08987429B2

公开(公告)日：2015-03-24

申请号：US13607961

申请日：2012-09-10

申请人： Hyo Young Lee , Luyang Wang

发明人： Hyo Young Lee , Luyang Wang

IPC分类号： C07F5/00 , C02F1/28 , C07F7/10 , C07D493/22

CPC分类号： C07F5/00 , A61K49/105 , C07D493/22 , C07F5/003

摘要： Disclosed herein is a GO-Gd-DTPA (gadolinium-diethylenetriamine pentaacetic-graphene oxide) complex, which is formed by an ester bond of graphene oxide (GO) and gadopentetic acid (Gd-DTPA). Since the GO-Gd-DTPA can stably exist in the body because it has high stability in water, it is expected that it can be effectively used as an MRI contrast agent.

摘要翻译： 本文公开了由氧化石墨烯（GO）和钆特酸（Gd-DTPA）的酯键形成的GO-Gd-DTPA（钆 - 二亚乙基三胺五乙酸 - 氧化石墨烯氧化物）络合物。由于GO-Gd-DTPA由于在水中的稳定性高而能够稳定地存在于体内，因此可以有效地将其用作MRI造影剂。