公开(公告)号：US20060135614A1

公开(公告)日：2006-06-22

申请号：US10520902

申请日：2003-07-08

申请人： Neeraj Garg ,  Mahmoud Ghadim ,  Thomas Ericsson ,  Lars Malm ,  Denis Ryono

发明人： Neeraj Garg ,  Mahmoud Ghadim ,  Thomas Ericsson ,  Lars Malm ,  Denis Ryono

IPC分类号： A61K31/198 ,  C07C237/28

CPC分类号： C07C235/52 ,  C07C235/34

摘要： This invention relates to novel compounds, which are thyroid receptor ligands, and to methods of preparing such compounds. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described herein is administered in a therapeutically effective amount.

摘要翻译： 本发明涉及作为甲状腺受体配体的新化合物及其制备方法。 此外，提供了一种用于预防，抑制或治疗与代谢功能障碍相关或与T3调节基因的表达相关的疾病或病症的方法，其中本文所述的化合物以治疗有效量施用。