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公开(公告)号:US09359281B2
公开(公告)日:2016-06-07
申请号:US14349962
申请日:2012-10-08
申请人: Pablo Vicente Escribá Ruiz , María Laura Martín , María Antònia Noguera Salvà , Xavier Busquets Xaubet , David López Jiménez , Maitane Ibarguren Aizpitarte , José Javier Soto Salvador , Miguel Yus Astiz
发明人: Pablo Vicente Escribá Ruiz , María Laura Martín , María Antònia Noguera Salvà , Xavier Busquets Xaubet , David López Jiménez , Maitane Ibarguren Aizpitarte , José Javier Soto Salvador , Miguel Yus Astiz
IPC分类号: A61K31/20 , C07C59/42 , C07C51/493
CPC分类号: C07C59/42 , C07B2200/07 , C07C51/493
摘要: This invention refers to the synthesis and purification of 2 hydroxide derivatives of fatty acids, as well as to the separation method of its enantiomers (or optic isomers) [−] y [+], to the enantiomers themselves, to pharmaceutical compositions which include them, and to their use as medicines, as well as to an in vitro method of diagnosis/prognosis and evaluation of the potential use of the molecules of the invention in different pathologies, as well as their use for the regulation of certain enzymes and the study of their activity and effects.
摘要翻译: 本发明涉及2种脂肪酸氢氧化物衍生物的合成和纯化,以及其对映异构体(或视觉异构体)[ - ] y [+]与对映异构体本身对包括它们的药物组合物的分离方法 ,以及它们作为药物的用途,以及用于诊断/预后的体外方法和评价本发明的分子在不同病理学中的潜在用途,以及它们用于调节某些酶和研究的用途 的活动和效果。
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公开(公告)号:US20140288176A1
公开(公告)日:2014-09-25
申请号:US14349962
申请日:2012-10-08
申请人: Pablo Vicente Escribá Ruiz , Gwndolyn Barceló Coblijn , María Laura Martín , Silvia Terés Jiménez , María Antònia Noguera Salvà , Xavier Busquets Xaubet , David López Jiménez , Maitane Ibarguren Aizpitarte , José Javier Soto Salvador , Miguel Yus Astiz
发明人: Pablo Vicente Escribá Ruiz , Gwndolyn Barceló Coblijn , María Laura Martín , Silvia Terés Jiménez , María Antònia Noguera Salvà , Xavier Busquets Xaubet , David López Jiménez , Maitane Ibarguren Aizpitarte , José Javier Soto Salvador , Miguel Yus Astiz
IPC分类号: C07C59/42
CPC分类号: C07C59/42 , C07B2200/07 , C07C51/493
摘要: This invention refers to the synthesis and purification of 2 hydroxide derivatives of fatty acids, as well as to the separation method of its enantiomers (or optic isomers) [−] y [+], to the enantiomers themselves, to pharmaceutical compositions which include them, and to their use as medicines, as well as to an in vitro method of diagnosis/prognosis and evaluation of the potential use of the molecules of the invention in different pathologies, as well as their use for the regulation of certain enzymes and the study of their activity and effects.
摘要翻译: 本发明涉及2种脂肪酸氢氧化物衍生物的合成和纯化,以及其对映异构体(或视觉异构体)[ - ] y [+]与对映异构体本身对包括它们的药物组合物的分离方法 ,以及它们作为药物的用途,以及用于诊断/预后的体外方法和评价本发明的分子在不同病理学中的潜在用途,以及它们用于调节某些酶和研究的用途 的活动和效果。
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