Pharmaceutical dosage forms with impeded extractability of a sympathomimetic
    3.
    发明申请
    Pharmaceutical dosage forms with impeded extractability of a sympathomimetic 审中-公开
    具有阻碍的交感神经的可提取性的药物剂型

    公开(公告)号:US20060062847A1

    公开(公告)日:2006-03-23

    申请号:US11225176

    申请日:2005-09-14

    IPC分类号: A61K9/20 C07C67/36

    摘要: A solid oral pharmaceutical dosage form of a sympathomimetic with impeded extractability of the sympathomimetic, comprising I) a sympathomimetic (component I) II) an excipient mixture (component II) composed of a) 5 to 50% by weight of hydroxyalkylcelluloses or alkylcelluloses or mixtures thereof b) 5 to 70% by weight of xanthan c) 5 to 50% by weight of an alkaline earth metal salt of a C10-C30 fatty acid d) 10 to 70% by weight of an alkali metal or alkaline earth metal salt of a mineral acid, of a sulfonic acid or of a C2-C6 carboxylic acid or mixtures thereof, where the total of components a) to d) is 100% by weight, where the ratio of active ingredient to excipient mixture II) is from 1:2 to 3:1 by weight.

    摘要翻译: 包含I)拟交感神经元(组分I)II)赋形剂混合物(组分II)的固体口服药物剂型,其具有妨碍所述交感神经活性的可提取性,其包含a)5至50重量%的羟烷基纤维素或烷基纤维素或混合物 b)5〜70重量%的呫吨