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公开(公告)号:US09308254B2
公开(公告)日:2016-04-12
申请号:US13579555
申请日:2011-02-17
申请人: Mervyn Maze , Marc Feldman , Niccolo Terrando , Mario Cibelli , Daqing Ma , Michael Fertleman
发明人: Mervyn Maze , Marc Feldman , Niccolo Terrando , Mario Cibelli , Daqing Ma , Michael Fertleman
IPC分类号: A61K39/395 , A61K38/00 , C07K14/525 , C07K16/24 , A61K39/00
CPC分类号: C07K16/241 , A61K31/546 , A61K31/713 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K14/525 , C07K2317/76 , C12N15/113 , C12N2310/11 , C12N2310/14
摘要: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
摘要翻译: 本发明提供了在计划的炎性触发之后预防或减少患者的认知衰退的方法,用途和试剂。 这种计划的炎性触发可以是外科手术或化疗。 本发明还提供了用于减少患有认知障碍的患者的认知衰退的方法,用途和试剂,其中所述患者已经暴露于炎性触发。 还提供药物组合物和试剂盒。
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公开(公告)号:US20130084299A1
公开(公告)日:2013-04-04
申请号:US13579555
申请日:2011-02-17
申请人: Mervyn Maze , Marc Feldman , Niccolo Terrando , Mario Cibelli , Daqing Ma , Michael Fertleman
发明人: Mervyn Maze , Marc Feldman , Niccolo Terrando , Mario Cibelli , Daqing Ma , Michael Fertleman
IPC分类号: A61K39/395
CPC分类号: C07K16/241 , A61K31/546 , A61K31/713 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K14/525 , C07K2317/76 , C12N15/113 , C12N2310/11 , C12N2310/14
摘要: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
摘要翻译: 本发明提供了在计划的炎性触发之后预防或减少患者的认知衰退的方法,用途和试剂。 这种计划的炎性触发可以是外科手术或化疗。 本发明还提供了用于减少患有认知障碍的患者的认知衰退的方法,用途和试剂,其中所述患者已经暴露于炎性触发。 还提供药物组合物和试剂盒。
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