公开(公告)号：US20150031600A1

公开(公告)日：2015-01-29

申请号：US13994482

申请日：2011-12-14

申请人： Anton Peter Jacob Middelberg ,  Mirjana Dimitrijev-Dwyer ,  Michael Brech

发明人： Anton Peter Jacob Middelberg ,  Mirjana Dimitrijev-Dwyer ,  Michael Brech

IPC分类号： C11D3/386 ,  C07K14/00

CPC分类号： C11D3/386 ,  C07K14/00 ,  C07K14/001 ,  C11D3/3719 ,  C11D3/38

摘要： The present invention relates to designed polypeptide biosurfactants that may be prepared by recombinant technology in commercially useful amounts and purified by simple non-chromatographic methods. The designed polypeptide biosurfactants comprise at least one stimuli-responsive amino acid residue or at least one glutamine or asparagine residue and may be useful in modulating the stability of a foam, alone or in combination with an α-helical peptide. The designed polypeptide biosurfactant may be useful in the formation and collapse of foams in foods, beverages, pharmaceuticals, personal care products, cosmetics, cleaning products, mineral recovery, bioremediation, oil recovery and laundry products. The designed biosurfactants may also be useful in recombinant production and purification of peptides, polypeptides and proteins.

摘要翻译： 本发明涉及可以通过重组技术以商业上有用的量制备并通过简单的非色谱方法纯化的设计的多肽生物表面活性剂。 设计的多肽生物表面活性剂包含至少一种刺激响应性氨基酸残基或至少一种谷氨酰胺或天冬酰胺残基，并且可用于单独或与α-螺旋肽组合调节泡沫的稳定性。 设计的多肽生物表面活性剂可用于食品，饮料，药物，个人护理产品，化妆品，清洁产品，矿物回收，生物修复，油回收和洗衣产品中的泡沫的形成和塌陷。 设计的生物表面活性剂也可用于肽，多肽和蛋白质的重组生产和纯化。