-
公开(公告)号:US20110172263A1
公开(公告)日:2011-07-14
申请号:US13120074
申请日:2009-09-17
IPC分类号: A61K31/437 , C07D221/06 , A61P11/00 , A61P29/00 , A61P19/00 , A61P7/00 , A61P3/10 , A61P37/00
CPC分类号: C07D471/04
摘要: Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.
摘要翻译: 式I化合物是PGD2受体CRTH2的拮抗剂,因此可用于治疗和/或预防CRTH2介导的疾病如哮喘。
-
公开(公告)号:US08546422B2
公开(公告)日:2013-10-01
申请号:US13120067
申请日:2009-09-17
IPC分类号: C07D491/00 , C07D498/00 , C07D513/00 , C07D515/00 , C07D471/00
CPC分类号: C07D471/14
摘要: Compounds of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.
摘要翻译: 式I化合物是PGD2受体CRTH2的拮抗剂,因此可用于治疗和/或预防CRTH2介导的疾病如哮喘。
-
公开(公告)号:US08637671B2
公开(公告)日:2014-01-28
申请号:US13120074
申请日:2009-09-17
IPC分类号: C07D471/04 , A61K31/437
CPC分类号: C07D471/04
摘要: Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.
摘要翻译: 式I化合物是PGD2受体CRTH2的拮抗剂,因此可用于治疗和/或预防CRTH2介导的疾病如哮喘。
-
公开(公告)号:US20110178115A1
公开(公告)日:2011-07-21
申请号:US13120067
申请日:2009-09-17
IPC分类号: C07D471/04 , A61K31/4353
CPC分类号: C07D471/14
摘要: Compounds of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.
摘要翻译: 式I化合物是PGD2受体CRTH2的拮抗剂,因此可用于治疗和/或预防CRTH2介导的疾病如哮喘。
-
-
-