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公开(公告)号:US20130190487A1
公开(公告)日:2013-07-25
申请号:US12524346
申请日:2008-01-24
申请人: Anton Stimac , Barbara Mohar , Michel Stephan , Mojca Bevc , Rok Zupet , Andrej Gartner , Vesna Kroselj , Matej Smrkolj , Davor Kidemet , Gregor Sedmak , PRIMOZ BENKIC , ALEN KLJAJIC , MIHA PLEVNIK
发明人: Anton Stimac , Barbara Mohar , Michel Stephan , Mojca Bevc , Rok Zupet , Andrej Gartner , Vesna Kroselj , Matej Smrkolj , Davor Kidemet , Gregor Sedmak , PRIMOZ BENKIC , ALEN KLJAJIC , MIHA PLEVNIK
IPC分类号: C07D205/08
CPC分类号: C07D205/08 , C07D403/06
摘要: The present invention relates to the method of preparing of ezetimibe and in particular to novel intermediates for its synthesis and an improved process for preparing such intermediates. Said intermediates may be obtained in high yields and purity in a fast and cost efficient manner. The present invention relates to a novel crystalline form of ezetimibe as well.
摘要翻译: 本发明涉及依泽替米贝的制备方法,特别涉及其合成的新型中间体以及制备这种中间体的改进方法。 所述中间体可以快速且成本有效的方式以高产率和纯度获得。 本发明还涉及一种新型的依泽替米贝的结晶形式。