公开(公告)号：US20120045779A1

公开(公告)日：2012-02-23

申请号：US13138483

申请日：2010-02-23

申请人： Yasuhito Abe ,  Motowo Nabeta ,  Masaharu Ito

发明人： Yasuhito Abe ,  Motowo Nabeta ,  Masaharu Ito

IPC分类号： G01N33/573 ,  C07K16/40 ,  C07K16/28

CPC分类号： G01N33/57488 ,  G01N33/6893 ,  G01N2800/364

摘要： It is an object of the present invention to provide: a method for determining endometriosis, in which a blood sample from a subject can be used, and which is capable of determining endometriosis with higher sensitivity and higher precision than those of a conventional method using only a conventional endometriosis marker such as CA125; and a diagnostic kit for carrying out the method of the present invention. The method for determining endometriosis according to the present invention comprises: a step of analyzing an expression of at least one selected from among an anti-syntaxin autoantibody, an anti-PDIK1L autoantibody and an anti-enolase autoantibody; and a step of determining the presence or absence of the onset of endometriosis based on results of said expression analysis.

摘要翻译： 本发明的目的是提供：一种用于确定子宫内膜异位症的方法，其中可以使用来自受试者的血液样本，并且能够比仅使用传统方法的更高灵敏度和更高精度确定子宫内膜异位症 常规的子宫内膜异位症标志物如CA125; 以及用于实施本发明的方法的诊断试剂盒。 根据本发明的用于确定子宫内膜异位症的方法包括：分析选自以下的至少一种的表达的步骤：抗神经炎蛋白自身抗体，抗-PDIK1L自身抗体和抗 - 烯醇酶自身抗体; 以及基于所述表达分析的结果确定子宫内膜异位症发作的存在或不存在的步骤。