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公开(公告)号:US20240043900A1
公开(公告)日:2024-02-08
申请号:US18463864
申请日:2023-09-08
申请人: Nobell Foods, Inc.
发明人: Viviane LANQUAR , Magi EL-RICHANI , Leyla HATHWAIK , Yaxin WANG
CPC分类号: C12P21/06 , C12N9/6424 , C12N9/6483 , C12Y304/21009 , A23C20/00 , A23J3/10 , C07K14/4732 , C07K2319/00
摘要: Provided herein are compositions and methods for producing milk proteins, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure provides recombinant fusion proteins comprising at least first protein and a second protein, wherein at least one of the first protein and the second protein is a milk protein, or fragment thereof. The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
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公开(公告)号:US20240035041A1
公开(公告)日:2024-02-01
申请号:US18066604
申请日:2022-12-15
申请人: Nobell Foods, Inc.
发明人: Magi EL-RICHANI , Shu LI
CPC分类号: C12N15/8257 , C07K14/4732 , C12N9/2462 , C07K14/76 , C12Y111/01007 , C07K14/4717 , C07K14/765 , C12N9/0065 , C07K14/79 , A23J1/00 , C12N2800/22
摘要: The disclosure describes a transgenic dicot or monocot plant having bovine milk protein(s) (e.g., bovine casein) and methods of producing the transgenic dicot or monocot plant containing bovine milk protein(s). These transgenic dicot or monocot plants can express and produce bovine milk protein(s) (e.g., bovine casein). The methods involve introducing a recombinant DNA construct expressing a bovine milk protein into a dicot or monocot plant, obtaining the dicot or monocot plant containing the bovine milk protein(s) from a recombinant DNA construct, cultivating and harvesting the transgenic dicot or monocot plant, and extracting and purifying the bovine milk protein(s) (e.g., bovine casein) from transgenic dicot or monocotyledonous plants. The disclosure also describes food compositions comprising milk proteins produced using the transgenic dicot or monocot plants described herein.
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公开(公告)号:US20230265139A1
公开(公告)日:2023-08-24
申请号:US18192519
申请日:2023-03-29
申请人: Nobell Foods, Inc.
CPC分类号: C07K14/4732 , A23C20/00 , A23J3/10 , C07K2319/00
摘要: Provided herein are compositions and methods for producing milk proteins, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure provides recombinant fusion proteins comprising at least first protein and a second protein, wherein at least one of the first protein and the second protein is a milk protein, or fragment thereof: The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
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公开(公告)号:US20240177797A1
公开(公告)日:2024-05-30
申请号:US18519995
申请日:2023-11-27
申请人: Nobell Foods, Inc.
发明人: Viviane LANQUAR , Leyla HATHWAIK , Yaxin WANG
IPC分类号: G16B15/10
CPC分类号: G16B15/10
摘要: Provided herein are compositions and methods for stabilizing RNA, increasing protein expression, and combinations thereof. Also provided are compositions and methods for utilizing stabilized RNA or increased protein levels to generate chordate proteins in a host cell, such as a plant cell.
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公开(公告)号:US11952606B2
公开(公告)日:2024-04-09
申请号:US18192519
申请日:2023-03-29
申请人: Nobell Foods, Inc.
CPC分类号: C12P21/06 , A23C20/00 , A23J3/10 , C07K14/4732 , C12N9/6424 , C12N9/6483 , C12Y304/21009 , C07K2319/00
摘要: Provided herein are compositions and methods for producing milk proteins, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in alternative food compositions. The disclosure provides recombinant fusion proteins comprising at least a first casein protein and a second casein protein. The disclosure also provides methods for producing the recombinant fusions proteins, and alternative food compositions comprising the same.
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公开(公告)号:US20230203556A1
公开(公告)日:2023-06-29
申请号:US18064199
申请日:2022-12-09
申请人: Nobell Foods, Inc.
发明人: Viviane LANQUAR , Magi EL-RICHANI , Leyla HATHWAIK , Yaxin WANG
CPC分类号: C12P21/06 , C12N9/6424 , C12Y304/21009 , C12N9/6483
摘要: Provided herein are compositions and methods for producing milk proteins, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure further teaches methods of increasing the production/accumulation of casein proteins in host cells by co-expressing a kinase capable of phosphorylating the casein protein. Specifically, the disclosure provides host cells comprising a heterologous casein protein and a heterologous casein. Stable transgenic plants expressing heterologous caseins and heterologous kinase proteins are also provided. In some embodiments, the heterologous casein proteins of the disclosure are contained within fusion proteins comprising at least first protein and a second protein, wherein at least one of the first protein and the second protein is a milk protein, or fragment thereof. The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
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公开(公告)号:US20240102072A1
公开(公告)日:2024-03-28
申请号:US18538150
申请日:2023-12-13
申请人: Nobell Foods, Inc.
CPC分类号: C12P21/06 , A23C20/00 , A23J3/10 , C07K14/4732 , C12N9/6424 , C12N9/6483 , C12Y304/21009 , C07K2319/00
摘要: Provided herein are compositions and methods for producing milk proteins, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure provides recombinant fusion proteins comprising at least first protein and a second protein, wherein at least one of the first protein and the second protein is a milk protein, or fragment thereof. The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
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公开(公告)号:US20220372504A1
公开(公告)日:2022-11-24
申请号:US17851624
申请日:2022-06-28
申请人: Nobell Foods, Inc.
发明人: Viviane LANQUAR , Magi EL-RICHANI
摘要: Provided herein are compositions and methods for producing milk proteins in plants, which allow for safe, sustainable and humane production of milk proteins for commercial use, such as use in food compositions. The disclosure provides recombinant fusion proteins comprising a milk protein, or fragment thereof and a structured mammalian, avian, plant, or fungal protein, or fragment thereof. The disclosure also provides methods for producing the recombinant fusions proteins, and food compositions comprising the same.
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公开(公告)号:US20220098259A1
公开(公告)日:2022-03-31
申请号:US17493100
申请日:2021-10-04
申请人: Nobell Foods, Inc.
发明人: Viviane LANQUAR , Magi EL-RICHANI
IPC分类号: C07K14/47
摘要: Provided herein are compositions and methods for producing recombinant milk proteins, as well as food compositions comprising the same. In aspects, the recombinant milk proteins of the disclosure are recombinant fusion proteins comprising casein and beta-lactoglobulin.
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公开(公告)号:US12077798B2
公开(公告)日:2024-09-03
申请号:US18538150
申请日:2023-12-13
申请人: Nobell Foods, Inc.
CPC分类号: C12P21/06 , A23C20/00 , A23J3/10 , C07K14/4732 , C12N9/6424 , C12N9/6483 , C12Y304/21009 , C07K2319/00
摘要: Provided herein are food compositions comprising recombinant fusion proteins and methods for producing the same, which allow for safe, sustainable and humane production of milk proteins for commercial use. The disclosure provides recombinant fusion proteins comprising at least first casein milk protein and a second zein protein.
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