公开(公告)号：US20060235076A1

公开(公告)日：2006-10-19

申请号：US10543336

申请日：2004-01-28

申请人： Tomihiko Higuchi ,  Hirofumi Shibata ,  Yoichi Sato ,  Nobuhisa Takaishi ,  Kazuyoshi Kawazoe ,  Kotaro Murakami

发明人： Tomihiko Higuchi ,  Hirofumi Shibata ,  Yoichi Sato ,  Nobuhisa Takaishi ,  Kazuyoshi Kawazoe ,  Kotaro Murakami

IPC分类号： A61K31/235

CPC分类号： A61K31/546 ,  A61K31/235 ,  A61K31/353 ,  A61K31/43 ,  A61K31/431 ,  A61K31/545 ,  A61K36/48 ,  A61K2300/00

摘要： The invention relates to a therapy of an infection with a drug resistant bacterium wherein a characteristic of multivalent phenol derivatives and/or extracts from “Tara” which enhance the activity of β-lactam antibiotics on the drug resistant bacteria is utilized. Specifically, the invention relates to an enhancer of β-lactam antibiotics comprising a multivalent phenol derivative or its pharmaceutically acceptable salt, a pharmaceutical composition comprising a β-lactam antibiotic and a multivalent phenol derivative and/or extract from “Tara” for the therapy of an infection with a drug resistant bacterium, a disinfectant for the same, and a functional food comprising a multivalent phenol derivative and/or extract from “Tara”.

摘要翻译： 本发明涉及一种耐药细菌感染的治疗方法，其中利用了增强β-内酰胺抗生素对耐药细菌活性的“塔拉”多价酚衍生物和/或提取物的特征。 具体地，本发明涉及包含多价酚衍生物或其药学上可接受的盐的β-内酰胺抗生素增强剂，包含β-内酰胺抗生素和多价酚衍生物的药物组合物和/或“塔拉”用于治疗 耐药细菌感染，其消毒剂，以及包含多价酚衍生物和/或“塔拉”提取物的功能性食品。