公开(公告)号：US5236423A

公开(公告)日：1993-08-17

申请号：US895193

申请日：1992-06-05

申请人： Thomas W. Mix ,  Ernesto E. Blanco ,  Norman Rosskothen ,  Maria L. Hernandez ,  Gordon C. Vineyard ,  Liem T. Vu

发明人： Thomas W. Mix ,  Ernesto E. Blanco ,  Norman Rosskothen ,  Maria L. Hernandez ,  Gordon C. Vineyard ,  Liem T. Vu

IPC分类号： A61B1/31 ,  A61M25/00 ,  A61M25/01

CPC分类号： A61B1/00151 ,  A61B1/31 ,  A61M25/0111 ,  A61M25/0009 ,  Y10S600/92

摘要： One aspect is a method for inserting an instrument into the gastrointestinal tract of a mammal, by emplacing at least a portion of a flexible liner to form within the intestine an inner tube within an outer tube, the inner tube defining a lumen lying within the intestine and having a distal end accessible via the anal opening from outside the body of the mammal, and thereafter passing the instrument into the lumen via its distal end. Another aspect is the combination of an elongate evertible liner, a liner support chamber having a proximal port and a distal port, the liner having its two ends attached respectively at the ports, and a pressurizer for increasing the pressure within the chamber to cause the liner to be everted, the liner comprising a material characterized by having a wall thickness to diameter ratio and a zero strain elasticity modulus whose product is less than 4.0 lb/inch.sup.2, preferably less than 1.0 lb/inch.sup.2, and a wall thickness to diameter ratio and a 100% strain modulus of elasticity whose product is greater than 0.5 lb/inch.sup.2, preferably greater than 2.0 lb/inch.sup.2. In another aspect, a layer of lubricous material, such as polyvinylpyrrolidone (PVP), is directly bonded to a surface of a layer of elastomeric material (such as polyurethane) without the use of adhesive materials between the layers. The resultant PVP-coated sheet is formed into the flexible liner. Yet another aspect is several devices for emplacing the liner in the intestine.

摘要翻译： 一个方面是用于将器械插入哺乳动物的胃肠道中的方法，通过将至少一部分柔性衬垫放置在肠内，在内管内部形成内管，内管限定位于肠内的内腔 并且具有通过肛门开口从哺乳动物的身体外部接近的远端，然后经由其远端将器械通入内腔。 另一方面是细长的可翻转衬垫，具有近端口和远端口的衬垫支撑室的组合，衬垫的两端分别在端口附近，以及用于增加腔室内的压力以使衬垫 该衬垫包括材料，其特征在于具有壁厚与直径的比率和零应变弹性模量，其零度应变弹性模量小于4.0磅/英寸2，优选小于1.0磅/英寸2，壁厚比和 产品的100％应变弹性模量大于0.5磅/英寸2，最好大于2.0磅/英寸2。 另一方面，一层润滑材料，例如聚乙烯吡咯烷酮（PVP），直接粘合到一层弹性体材料（如聚氨酯）的表面，而不用层之间使用粘合剂材料。 所得到的PVP涂层片材形成柔性衬垫。 另一方面是用于在肠中放置衬垫的若干装置。