公开(公告)号：US20100159445A1

公开(公告)日：2010-06-24

申请号：US11816159

申请日：2007-03-01

申请人： Michael Lustig ,  Oliver Böcher ,  Winfried Albert

发明人： Michael Lustig ,  Oliver Böcher ,  Winfried Albert

IPC分类号： C12Q1/68

CPC分类号： G01N33/5308 ,  G01N33/57484

摘要： The present invention concerns a method for the individual staging of the tumor disease of an individual cancer patient, a method for the individual decision on the method of treatment as well as a method for treating a cancer patient as well as their use in the treatment of various cancer diseases like colorectal tumor, prostate tumor, breast tumor, lung tumor, as primary tumors, tumor relapse and/or metastases. The present invention further provides a new prognosis factor in cancer treatment. This inventive method includes the step of analyzing at least one disseminated tumor cell present in a sample taken from a patient for the expression of at least one mRNA of at least one of growth factors, growth factor receptors and tumor associated transcripts.

摘要翻译： 本发明涉及个体癌症患者肿瘤疾病个体分期的方法，个体决定治疗方法的方法以及治疗癌症患者的方法及其在治疗中的用途 各种癌症如结肠直肠肿瘤，前列腺肿瘤，乳腺肿瘤，肺肿瘤，原发性肿瘤，肿瘤复发和/或转移。 本发明进一步提供了癌症治疗中的新的预后因子。 本发明的方法包括分析存在于患者中的样品中至少一种弥散性肿瘤细胞以表达至少一种生长因子，生长因子受体和肿瘤相关转录物的mRNA的步骤。