公开(公告)号：US20080287511A1

公开(公告)日：2008-11-20

申请号：US11814617

申请日：2006-01-26

申请人： Jan Heeres ,  Paulus Joannes Lewi ,  Paul Adriaan Jan Janssen ,  Kathleen Marie Jeanne Alice Vlaminck ,  Pierre Josef Hektor Valere Ottevaere ,  Oscar Franz Joseph Vanparijs ,  Frank Xavier Jozef Herwig Arts

发明人： Jan Heeres ,  Paulus Joannes Lewi ,  Paul Adriaan Jan Janssen ,  Kathleen Marie Jeanne Alice Vlaminck ,  Pierre Josef Hektor Valere Ottevaere ,  Oscar Franz Joseph Vanparijs ,  Frank Xavier Jozef Herwig Arts

IPC分类号： A61K31/429 ,  C07D513/02 ,  A61P33/14

CPC分类号： C07D513/04

摘要： The present invention relates to the novel anthelmintic compound tetrahydro-furan-2-carboxylic acid-[3-(2,3,5,6-tetrahydro-imidazo[2,1-b]thiazol-6-yl)-phenyl]-amide and the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, as well as pharmaceutical compositions comprising said novel compound, processes for preparing said compound and compositions, and the use thereof as a medicine, in particular in treatment, control and prevention of endo- and ectoparasite infections in warm-blooded animals.

摘要翻译： 本发明涉及新型驱肠虫化合物四氢 - 呋喃-2-羧酸 - [3-（2,3,5,6-四氢 - 咪唑并[2,1-b]噻唑-6-基） - 苯基] 酰胺和其药学上可接受的酸加成盐及其立体化学异构形式，以及包含所述新化合物的药物组合物，制备所述化合物和组合物的方法及其作为药物的用途，特别是在治疗，控制和预防 温血动物的内寄生虫和外寄生虫感染。