公开(公告)号：US20050250734A1

公开(公告)日：2005-11-10

申请号：US10979329

申请日：2004-11-02

申请人： Abel Moreyra ,  Ashraf Koraym ,  Alan Wilson ,  Owen Carryl

发明人： Abel Moreyra ,  Ashraf Koraym ,  Alan Wilson ,  Owen Carryl

IPC分类号： A61K31/216 ,  A61K31/225 ,  A61K31/366 ,  A61K31/40 ,  A61K31/401 ,  A61K31/715 ,  A61K31/717 ,  A61K36/48 ,  A61K36/68 ,  A61K36/899 ,  A61K45/06

CPC分类号： A61K31/366 ,  A61K31/216 ,  A61K31/225 ,  A61K31/40 ,  A61K31/401 ,  A61K31/715 ,  A61K31/717 ,  A61K36/48 ,  A61K36/68 ,  A61K36/899 ,  A61K45/06 ,  A61K2300/00

摘要： Disclosed herein are methods of treating a condition associated with elevated cholesterol levels are provided, comprising administering to a mammal in need of such treatment a safe and effective amount of a cholesterol biosynthesis inhibitor and a soluble fiber. Further disclosed herein are kits comprising a first composition comprising a cholesterol biosynthesis inhibitor selected from the group consisting of HMG CoA reductase inhibitors, HMG CoA synthase inhibitors, and mixtures thereof; and a second composition comprising a soluble fiber. Even further described are compositions comprising a cholesterol biosynthesis inhibitor selected from the group consisting of HMG CoA reductase inhibitors, HMG CoA synthase inhibitors, and mixtures thereof; and a soluble fiber.

摘要翻译： 本文公开了治疗与升高的胆固醇水平相关的病症的方法，包括向需要这种治疗的哺乳动物施用安全有效量的胆固醇生物合成抑制剂和可溶性纤维。 本文进一步公开的是包含第一组合物的试剂盒，其包含选自HMG CoA还原酶抑制剂，HMG CoA合成酶抑制剂及其混合物的胆固醇生物合成抑制剂; 和包含可溶性纤维的第二组合物。 甚至进一步描述的是包含选自HMG CoA还原酶抑制剂，HMG CoA合成酶抑制剂及其混合物的胆固醇生物合成抑制剂的组合物; 和可溶性纤维。