公开(公告)号：US20210299071A1

公开(公告)日：2021-09-30

申请号：US17264882

申请日：2019-08-15

申请人： PHARMACYL AB

发明人： Anders BJÖRK ,  Gunnar HEDLUND

IPC分类号： A61K31/167 ,  A61P19/02 ,  A61P1/04

摘要： A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutical composition comprising the compound. The compound is useful for the treatment a disease resulting from pathologic inflammation, such as inflammatory bowel disease, psoriasis or rheumatoid arthritis.

公开(公告)号：US20210236441A1

公开(公告)日：2021-08-05

申请号：US17158117

申请日：2021-01-26

申请人： PHARMACYL AB

发明人： Anders BJÖRK ,  Gunnar HEDLUND

IPC分类号： A61K31/167 ,  A61P19/02

摘要： A method for the treatment a disease resulting from spondyloarthritis, such as axial spondyloarthritis, psoriatic arthritis and enteropathic arthritis, by administering, to a mammal in need of such treatment, a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof.

公开(公告)号：US11717500B2

公开(公告)日：2023-08-08

申请号：US17158117

申请日：2021-01-26

申请人： PHARMACYL AB

发明人： Anders Björk ,  Gunnar Hedlund

IPC分类号： A61K31/167 ,  A61P19/02

CPC分类号： A61K31/167 ,  A61P19/02

摘要： A method for the treatment a disease resulting from spondyloarthritis, such as axial spondyloarthritis, psoriatic arthritis and enteropathic arthritis, by administering, to a mammal in need of such treatment, a compound of formula (I)




or a pharmaceutically acceptable salt or solvate thereof.

公开(公告)号：US11896564B2

公开(公告)日：2024-02-13

申请号：US17264924

申请日：2019-08-15

申请人： PHARMACYL AB

发明人： Gunnar Hedlund ,  Anders Björk

IPC分类号： A61K31/166 ,  A61P1/04 ,  A61K45/06

CPC分类号： A61K31/166 ,  A61K45/06 ,  A61P1/04

摘要： A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, for use in combination with a 5-ASA agent, in the treatment of a disease resulting from pathologic inflammation. The combination of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof and 5-ASA agent and use of such combination. A kit-of-parts and a pharmaceutical composition comprising such a combination.

公开(公告)号：US20220087959A1

公开(公告)日：2022-03-24

申请号：US17264924

申请日：2019-08-15

申请人： PHARMACYL AB

发明人： Gunnar HEDLUND ,  Anders BJÖRK

IPC分类号： A61K31/166 ,  A61P1/04 ,  A61K45/06

摘要： A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, for use in combination with a 5-ASA agent, in the treatment of a disease resulting from pathologic inflammation. The combination of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof and 5-ASA agent and use of such combination. A kit-of-parts and a pharmaceutical composition comprising such a combination.