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公开(公告)号：US20210259634A1
公开(公告)日：2021-08-26
申请号：US17252639
申请日：2019-06-14
Applicant: PROTEUS DIGITAL HEALTH, INC.
Inventor： Jacques GINESTET , James HUTCHISON , Todd SCHOENBERGER , Jessica SZEJER , Iacopo FERRARI
IPC: A61B5/00
Abstract: A re-wearable physiological monitoring device includes a reusable component and a disposable component. The reusable component includes an electronics module and a latching system for latching the reusable component to the disposable component. The disposable component includes an adhesive patch to be adhered to a user's skin, two electrodes to receive electrical signals from the user's skin, a cradle for the reusable component to be latched on, and a battery to power the device. The disposable component may include a “battery disconnect switch” for disconnecting the battery when the reusable component is not latched on; a gasket for isolating each contact between the reusable component and the disposable component in a waterproof enclosure; and a printed contact within the disposable component that is resistant to scratching. A latching system for the device may include two snap fasteners, alignment feet for keeping the reusable component aligned with the disposable component, and an asymmetrical wall to prevent the reusable component from being placed on the disposable component in the wrong orientation. A method of assembling the reusable component by ultrasonic welding is also disclosed.
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公开(公告)号：US11044024B2
公开(公告)日：2021-06-22
申请号：US16719111
申请日：2019-12-18
Applicant: Proteus Digital Health, Inc.
Inventor： Mark Zdeblick , Timothy Robertson , Aleksandr Pikelny , Hooman Hafezi
IPC: H04B13/00 , A61B5/00 , H01Q1/27 , G16H20/10 , H04W4/80 , A61B5/07 , A61J3/00 , G06K7/10 , A61B5/1473
Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can be used in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.
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公开(公告)号：US20200342555A1
公开(公告)日：2020-10-29
申请号：US16680554
申请日：2019-11-12
Applicant: Proteus Digital Health, Inc.
Inventor： Todd THOMPSON , Lawrence ARNE , Fataneh OMIDVAR , Yashar BEHZADI , Robert DUCK , Lorenzo DICARLO , Gregory MOON
Abstract: A system and method are disclosed that track a deliverable to a user. The system includes an identifier or tag secured to the deliverable, a computer system for interrogating the identifier, and a personal device in communication with the computer system, wherein the personal device is held by the user at the time the user is administered the deliverable to detect the unique identity associated with the identifier device and confirms delivery of the deliverable to the user. The method includes attaching an identifiable tag that produces a unique signature to the deliverable, interrogating the tag at about the time of delivery to the user, and confirming that the user has been administered the deliverable through detecting the identifiable tag.
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公开(公告)号：US10797758B2
公开(公告)日：2020-10-06
申请号：US16244195
申请日：2019-01-10
Applicant: Proteus Digital Health, Inc.
Inventor： Alireza Shirvani , Mark Zdeblick , Jonathan Withrington
Abstract: Provided is an electronic device having a control device, a driver circuit coupled to the control device. The driver circuit is configured to alter conductance. A partial power source is coupled to the control device and is configured to provide a voltage potential difference to the control device and the driver circuit as a result of the partial power source being in contact with a conductive fluid. The partial power source includes a first material electrically coupled to the control device and a second material electrically coupled to the control device and electrically isolated from the first material. An inductor is coupled to the driver circuit. The driver circuit is configured to develop a current through the inductor. The magnitude of the current developed through the inductor is varied to produce an encoded signal that is remotely detectable by a receiver. Receivers to receive and decode also are disclosed.
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公开(公告)号：US10682071B2
公开(公告)日：2020-06-16
申请号：US15469052
申请日：2017-03-24
Applicant: Proteus Digital Health, Inc.
Inventor： Yashar Behzadi
Abstract: The disclosed system includes an ingestible event marker device configured to collect Ingestible Event Marker (IEM) data from a body of an individual and transmit a signal including the IEM data, wherein the IEM data include information associated with an ingestion event, a receiver adapted to be associated with the body of the individual and configured to receive the signal including the IEM data via the body of the individual, a hub to receive the IEM data from the receiver, and at least one IEM data system to receive the IEM data from the hub. The at least one IEM data system analyzes the IEM data and generates at least one metric based on the IEM data. The at least one IEM data system may further generate predictive information based on the at least one metric, wherein the predictive information is related to prediction of a state of the individual.
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Patent Agency Ranking
公开(公告)号：US10542909B2
公开(公告)日：2020-01-28
申请号：US15474811
申请日：2017-03-30
Applicant: Proteus Digital Health, Inc.
Inventor： Mark Zdeblick , Timothy Robertson , Aleksandr Pikelny , Hooman Hafezi
Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can be used in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.
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公开(公告)号：US20200001061A1
公开(公告)日：2020-01-02
申请号：US16264772
申请日：2019-02-01
Applicant: Proteus Digital Health, Inc.
Inventor： Timothy Robertson , Hooman Hafezi , Raymond Schmidt
IPC: A61M31/00
Abstract: The present invention discloses multiple approaches to preventing the capsule walls and other material from interfering with the performance of an electronic device once the device is activated by surrounding fluid. In accordance with the teachings of the present invention, a miniature ingestible device (MID) may be created using excipients and films. The MID, in accordance with various aspects of the present invention, will have a coating or laminating surrounding an electronic device and separating and isolating the device from the pharmaceutical product or drug within the capsule once the capsule is ingested as well as from the capsule itself as the capsule walls begin to collapse during the disintegration process.
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公开(公告)号：US20190191006A1
公开(公告)日：2019-06-20
申请号：US16026139
申请日：2018-07-03
Applicant: Proteus Digital Health, Inc.
Inventor： Andrew Thompson , Todd Thompson , Yashar Behzadi , Danielle Cojuangco Abraham , Robert Duck , Arna Ionescu , Ray Lee , Robin Suchan , William Turner , Veeraperumanallu Muralidharan , Erika Karplus , George Savage
CPC classification number: H04L67/306 , G06F19/3418 , G16H10/60 , G16H40/67 , H04W4/21 , H04W4/80
Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.
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公开(公告)号：US20190158151A1
公开(公告)日：2019-05-23
申请号：US16244195
申请日：2019-01-10
Applicant: Proteus Digital Health, Inc.
Inventor： Alireza Shirvani , Mark Zdeblick , Jonathan Withrington
Abstract: Provided is an electronic device having a control device, a driver circuit coupled to the control device. The driver circuit is configured to alter conductance. A partial power source is coupled to the control device and is configured to provide a voltage potential difference to the control device and the driver circuit as a result of the partial power source being in contact with a conductive fluid. The partial power source includes a first material electrically coupled to the control device and a second material electrically coupled to the control device and electrically isolated from the first material. An inductor is coupled to the driver circuit. The driver circuit is configured to develop a current through the inductor. The magnitude of the current developed through the inductor is varied to produce an encoded signal that is remotely detectable by a receiver. Receivers to receive and decode also are disclosed.
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公开(公告)号：US10238604B2
公开(公告)日：2019-03-26
申请号：US14570673
申请日：2014-12-15
Applicant: Proteus Digital Health, Inc.
Inventor： Hooman Hafezi , Timothy Robertson , Olivier Colliou , Mark Zdeblick
Abstract: Controlled activation identifiers for use in ingestible compositions, such as pharma-informatics enabled compositions, are provided. The identifiers include a controlled activation element that provides for activation of the identifier in response to the presence of a predetermined stimulus at a target site of interest. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
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