-
1.发明授权3-Phenyl-2-arylalkylthiopropionic acid derivatives as selective agonists of ppar-alpha 失效3-苯基-2-芳烷基硫代丙酸衍生物作为ppar-α的选择性激动剂公开(公告)号：US07276539B2
公开(公告)日：2007-10-02
申请号：US10499042
申请日：2002-12-18
IPC分类号： A61K31/10 , C07C309/66
CPC分类号： C07C323/56
摘要： A compound of formula I wherein R1 represents chloro, fluoro or hydroxy as well as optical isomers and racemates thereof as well as pharmaceutically acceptable salts, prodrugs, solvates and crystalline forms thereof, processes for preparing such compounds, their utility in treating clinical conditions associated with insulin resistance, methods for their therapeutic use and pharmaceutical compositions containing them.
摘要翻译： 式I的化合物，其中R 1表示氯，氟或羟基，以及其旋光异构体和外消旋体，以及其药学上可接受的盐，前药，溶剂合物和结晶形式，制备这些化合物的方法， 其用于治疗与胰岛素抵抗相关的临床病症，其治疗用途的方法和含有它们的药物组合物。
-
2.发明申请3-Phenyl-2-arylalkylthiopropionic acid derivatives as selective agonists of ppar-alpha 失效3-苯基-2-芳烷基硫代丙酸衍生物作为ppar-α的选择性激动剂公开(公告)号：US20050215630A1
公开(公告)日：2005-09-29
申请号：US10499042
申请日：2002-12-18
IPC分类号： A61K45/00 , A61K20060101 , A61K31/192 , A61K31/255 , A61K31/366 , A61K31/40 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , C07C20060101 , C07C309/66 , C07C319/20 , C07C323/56 , C07D20060101 , C07D221/18 , C07K14/705
CPC分类号： C07C323/56
摘要： A compound of formula (I); wherein R1 represents chloro, fluoro or hydroxy as well as optical isomers and racemates thereof as well as pharmaceutically acceptable salts, prodrugs, solvates and crystalline forms thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
摘要翻译： 式（I）化合物; 其中R 1表示氯，氟或羟基，以及其光学异构体和外消旋体，以及其药学上可接受的盐，前药，溶剂合物和结晶形式，用于制备这些化合物的方法， 在治疗包括脂质紊乱（血脂异常）在内的临床症状，不论是否与胰岛素抵抗相关，其治疗用途的方法和含有它们的药物组合物。
-
搜索结果
2 条记录 (耗时 0.01 秒)
