Animal Model for Toxicology and Dose Prediction
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    发明申请
    Animal Model for Toxicology and Dose Prediction 审中-公开
    毒理学和剂量预测动物模型

    公开(公告)号:US20120110682A1

    公开(公告)日:2012-05-03

    申请号:US13348479

    申请日:2012-01-11

    IPC分类号: A61K49/00 A61K51/00

    摘要: The invention relates to the use of fetal tissues to generate a tissue model in a non-human animal. The tissue model comprises target tissues allowed to progress through development in vivo in a non-human host in order to obtain tissues having a mature phenotype that can be used to assess toxicity and/or efficacy of an agent.

    摘要翻译: 本发明涉及胎儿组织在非人动物中产生组织模型的用途。 组织模型包括允许在非人宿主体内通过体内发育进展的靶组织,以获得可用于评估药物的毒性和/或功效的具有成熟表型的组织。