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公开(公告)号：US06238648B1
公开(公告)日：2001-05-29
申请号：US09276344
申请日：1999-03-25
IPC分类号： A61K716
摘要： The present invention relates to oral care compositions, including therapeutic rinses, tooth pastes and gels comprising a combination of a non-cariogenic carbohydrate and polyalcohol. This invention further relates to a method for treating or preventing conditions in the mouth that favor formation of tooth caries.
摘要翻译： 本发明涉及口腔护理组合物，包括治疗性漂洗剂，牙膏和凝胶，其包含非致龋碳水化合物和多元醇的组合。 本发明还涉及治疗或预防有利于牙龋形成的口腔状况的方法。
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2.发明授权Apparatus and methods for visual demonstration of dental erosion on simulated dental materials 有权用于模拟牙科材料牙科侵蚀的视觉展示的装置和方法公开(公告)号：US09087457B2
公开(公告)日：2015-07-21
申请号：US12874683
申请日：2010-09-02
CPC分类号： G09B23/283 , A61K6/0017 , B05D1/185 , B05D2350/65 , G09B19/0084
摘要： Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.
摘要翻译： 各种口腔护理产品如洁齿剂对预防牙齿侵蚀的比较效果可以使用模拟搪瓷来证明。 制备底物。 用于模拟牙釉质的矿物层通过在基底表面上的溶液生长而成核。 或者，矿物层可以在包含在沉积在基底表面上的金层上形成的自组装单层的模板上成核。 矿物层可以在非晶磷酸钙层上包含羟基磷灰石的均匀层或羟基磷灰石的薄薄单板。 然后任选地用口腔护理产品处理模拟的釉质并进行酸性攻击。 在酸攻击之后残留的矿物层的量说明了口腔护理产品在预防牙齿侵蚀方面的有效性或非有效性。
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3.发明申请APPARATUS AND METHODS FOR VISUAL DEMONSTRATION OF DENTAL EROSION ON SIMULATED DENTAL MATERIALS 有权模拟牙科材料对牙齿腐蚀的视觉演示的装置和方法公开(公告)号：US20110059425A1
公开(公告)日：2011-03-10
申请号：US12874683
申请日：2010-09-02
CPC分类号： G09B23/283 , A61K6/0017 , B05D1/185 , B05D2350/65 , G09B19/0084
摘要： Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.
摘要翻译： 各种口腔护理产品如洁齿剂对预防牙齿侵蚀的比较效果可以使用模拟搪瓷来证明。 制备底物。 用于模拟牙釉质的矿物层通过在基底表面上的溶液生长而成核。 或者，矿物层可以在包含在沉积在基底表面上的金层上形成的自组装单层的模板上成核。 矿物层可以在非晶磷酸钙层上包含羟基磷灰石的均匀层或羟基磷灰石的薄薄单板。 然后任选地用口腔护理产品处理模拟的釉质并进行酸性攻击。 在酸攻击之后残留的矿物层的量说明了口腔护理产品在预防牙齿侵蚀方面的有效性或非有效性。
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