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1.发明授权Process for the preparation of organotin compounds useful as cytotoxic agents 失效制备用作细胞毒性剂的有机锡化合物的方法
公开(公告)号：US5929238A
公开(公告)日：1999-07-27
申请号：US977947
申请日：1997-11-25
申请人： Sujit Roy , Purnima M. Samuel , Prakash V. Diwan , P. Kanta Rao , U. T. Bhalerao
发明人： Sujit Roy , Purnima M. Samuel , Prakash V. Diwan , P. Kanta Rao , U. T. Bhalerao
CPC分类号： C07F7/2284 , C07F7/2268
摘要： The present invention is drawn to complexes of dibenzyl-organotin compounds having nitrogen or sulfur containing heterocyclic ligands. Said complexes are useful as cytotoxic agents.
摘要翻译： 本发明涉及具有含氮或含硫杂环配位体的二苄基 - 有机锡化合物的络合物。 所述复合物可用作细胞毒性剂。
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公开(公告)号：US20110269790A1
公开(公告)日：2011-11-03
申请号：US13143272
申请日：2010-01-05
申请人： Shireesha Boyapati , Akkinepally Raghuram Rao , Banda Narsaiah , Prakash V. Diwan , Sistla Ramakrishna , Madhusudhana , Tallapally Yakaiah
发明人： Shireesha Boyapati , Akkinepally Raghuram Rao , Banda Narsaiah , Prakash V. Diwan , Sistla Ramakrishna , Madhusudhana , Tallapally Yakaiah
IPC分类号： A61K31/4365 , A61P19/00 , A61P35/00 , C07D409/02 , A61P3/10
CPC分类号： C07D495/04
摘要： The present invention provides compounds and pharmaceutically acceptable salts thereof methods for synthesizing thienopyridines and methods for inhibiting TNF-α activity for the treatment of cancer, asthma, arthritis, diabetes and inflammation. Provided are compounds of formula (I).
摘要翻译： 本发明提供了用于合成噻吩并吡啶的化合物及其药学上可接受的盐以及用于抑制TNF-α活性用于治疗癌症，哮喘，关节炎，糖尿病和炎症的方法。 提供式（I）的化合物。
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3.发明授权公开(公告)号：US07626025B2
公开(公告)日：2009-12-01
申请号：US10814777
申请日：2004-03-30
申请人： Yenamandra Venkateswarlu , Kodela Ravinder , Jhillu S. Yadav , Yandrapu Sarathkumar , Sistla Ramakrishna , Prakash V. Diwan , Janapala V. Rao , Ratnam Ramesh , Hartmut Laatsch
发明人： Yenamandra Venkateswarlu , Kodela Ravinder , Jhillu S. Yadav , Yandrapu Sarathkumar , Sistla Ramakrishna , Prakash V. Diwan , Janapala V. Rao , Ratnam Ramesh , Hartmut Laatsch
IPC分类号： C07D455/04 , A61K31/437
CPC分类号： C07D471/04
摘要： A novel β-carboline guanidine derivative tiruchenduramine (1) and its derivatives are disclosed. These compounds have been isolated from the Indian ascidian Synoicum macroglossum. These compounds are useful in the treatment of diabetic disorder by providing inhibition of α (alpha)glucosidase.
摘要翻译： 公开了一种新的β-咔啉胍衍生物噻菌灵多胺（1）及其衍生物。 这些化合物已经从印度的腹泻大鼠中分离出来。 通过提供α（α）葡糖苷酶的抑制，这些化合物可用于治疗糖尿病。
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公开(公告)号：US5877320A
公开(公告)日：1999-03-02
申请号：US774029
申请日：1996-12-27
IPC分类号： C07F7/22
CPC分类号： C07F7/2284 , C07F7/2268
摘要： The present invention is drawn to complexes of dibenzyl-organotin compounds having nitrogen or sulfur containing heterocyclic ligands. Said complexes are useful as cytotoxic agents.
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