公开(公告)号：US20070270598A1

公开(公告)日：2007-11-22

申请号：US11716045

申请日：2007-03-09

Applicant: Rajendra Bhakuni ,  Tarun Singh ,  Rinku Singh ,  Atul Kahol ,  Suman Khanuja

Inventor： Rajendra Bhakuni ,  Tarun Singh ,  Rinku Singh ,  Atul Kahol ,  Suman Khanuja

IPC: C07D313/06

CPC classification number: C07D493/18

Abstract: The present invention relates to an improved process for one pot conversion of artemisinin into artelinic acid, which reduces the three step (three pot) conversion of artemisinin to artelinic acid in one step (one pot). The process of preparation of artelinic acid involves stirring of artemisinin with sodium borohydride, catalyst, polyhydroxy compound or chlorotrimethylsilane or amberlyst-15 resin and methyl p-(hydroxymethyl) benzoate, filtration of undissolved, unwanted reaction products and finally stirring of the filtrate with alcoholic or aqueous alkali hydroxide.

Abstract translation: 本发明涉及一种将青蒿素转化成青蒿酸的一锅转化的改进方法，其将一步（一锅）中青蒿素的三步（三锅）转化率降低至青蒿酸。 木瓜酸的制备过程包括用硼氢化钠，催化剂，多羟基化合物或氯代三甲基硅烷或琥珀酸钠树脂和对羟基甲基苯甲酸甲酯搅拌青蒿素，过滤未溶解的不需要的反应产物，最后用酒精搅拌滤液 或碱性氢氧化碱水溶液。

公开(公告)号：US20070089211P1

公开(公告)日：2007-04-19

申请号：US11334333

申请日：2006-01-18

Applicant: Suman Khanuja ,  Shilpi Paul ,  Ajit Kumar Shasany ,  Anil Gupta ,  Mahendra Darokar ,  Madan Gupta ,  Ram Verma ,  Govind Ram ,  Anuraddha Kumar ,  Raj Lal ,  Ravi Bansal ,  Anil Singh ,  Rajendra Bhakuni ,  Sudeep Tandon

Inventor： Suman Khanuja ,  Shilpi Paul ,  Ajit Kumar Shasany ,  Anil Gupta ,  Mahendra Darokar ,  Madan Gupta ,  Ram Verma ,  Govind Ram ,  Anuraddha Kumar ,  Raj Lal ,  Ravi Bansal ,  Anil Singh ,  Rajendra Bhakuni ,  Sudeep Tandon

IPC: A01H5/00

CPC classification number: A01H6/14 ,  A01H5/02

Abstract: The present invention is related to the development of a novel, distinct high herb and artemisinin yielding genotype of Artemisia annua obtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way wherein the genotype is distinct, uniform and stably maintainable by continuous rouging of off types in the population using DNA marker at early seedling stage from nursery itself and suitable for commercial cultivation.

Abstract translation: 本发明涉及通过系统标记辅助育种获得的一种新颖，不同的高草药和青蒿素产生的​​青蒿素基因型的发展，随后以有条理的方式选择均匀群体，其中基因型是不同的，均匀的并且可持续地通过连续的维持 在幼苗本身早期苗期使用DNA标记对群体中的种类进行粗糙化，适合商业种植。

公开(公告)号：US20050223447P1

公开(公告)日：2005-10-06

申请号：US10811244

申请日：2004-03-26

Applicant: Suman Preet Khanuja ,  Shilpi Paul ,  Ajit Shasany ,  Anil Gupta ,  Mahendra Darokar ,  Madan Gupta ,  Ram Verma ,  Govind Ram ,  Anuraddha Kumar ,  Raj Lal ,  Ravi Bansal ,  Anil Singh ,  Rajendra Bhakuni ,  Sudeep Tandon

Inventor： Suman Preet Khanuja ,  Shilpi Paul ,  Ajit Shasany ,  Anil Gupta ,  Mahendra Darokar ,  Madan Gupta ,  Ram Verma ,  Govind Ram ,  Anuraddha Kumar ,  Raj Lal ,  Ravi Bansal ,  Anil Singh ,  Rajendra Bhakuni ,  Sudeep Tandon

IPC: A01H1/00 ,  A01H5/00 ,  A01H5/02 ,  C12N15/82 ,  C12N15/87

CPC classification number: A01H6/14 ,  A01H5/02

Abstract: The present invention is related to the development of a novel, distinct high herb and artemisinin yielding genotype of Artemisia annua obtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way wherein the genotype is distinct, uniform and stably maintainable by continuous rouging of off types in the population using DNA marker at early seedling stage from nursery itself and suitable for commercial cultivation.

Abstract translation: 本发明涉及通过系统标记辅助育种获得的一种新颖，不同的高草药和青蒿素产生的​​青蒿素基因型的发展，随后以有条理的方式选择均匀群体，其中基因型是不同的，均匀的并且可持续地通过连续的维持 在幼苗本身早期苗期使用DNA标记对群体中的种类进行粗糙化，适合商业种植。