公开(公告)号：US07491721B2

公开(公告)日：2009-02-17

申请号：US10844992

申请日：2004-05-12

Applicant: Sudershan Kumar Arora ,  Neelima Sinha ,  Rakesh Sinha ,  Ram Shankar Upadhyaya

Inventor： Sudershan Kumar Arora ,  Neelima Sinha ,  Rakesh Sinha ,  Ram Shankar Upadhyaya

IPC: A61K31/12 ,  A61K31/33 ,  A61K31/135 ,  A61K31/165 ,  A61K31/166

CPC classification number: A61K31/131 ,  A61K31/4409 ,  A61K31/496 ,  A61K31/4965 ,  A61K45/06 ,  A61K2300/00

Abstract: An antimycobacterial combination and composition for treating tuberculosis are described. The compounds used are N-(3-[[4-(3-trifluoromethylphenyl)piperazinyl]methyl]-2-methyl-5-phenyl-pyrrolyl)-4-pyridylcarboxamide of formula (I) or a pharmaceutically acceptable non-toxic salt thereof and an amount of one or more first line antitubercular drugs.

Abstract translation: 描述了用于治疗结核病的抗分支杆菌组合物和组合物。 使用的化合物是式（I）的N-（3 - [[4-（3-三氟甲基苯基）哌嗪基]甲基] -2-甲基-5-苯基 - 吡咯基）-4-吡啶基甲酰胺或药学上可接受的无毒盐 和一种或多种一线抗结核药物。