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1.发明申请公开(公告)号：US20060210620A1
公开(公告)日：2006-09-21
申请号：US10542587
申请日：2004-01-21
CPC分类号： A61K31/4178 , A61K9/1635 , A61K9/2077 , A61K31/4174
摘要： The technical field of the invention relates to spray dried, co-precipitate amorphous losartan dosage forms that are stable over time and processes for their preparation. The processes stabilize the amorphous losartan. The process includes preparing an aqueous solution of losartan and one or more hydrophilic polymers; and spray drying the aqueous solution of losartan and one or more hydrophilic polymers to form a mixture. The amorphous losartan and one or more hydrophilic polymers are co-precipitated from the aqueous solution.
摘要翻译： 本发明的技术领域涉及随时间稳定的喷雾干燥，共沉淀的无定形氯沙坦剂型，其制备方法。 该方法稳定无定形氯沙坦。 该方法包括制备氯沙坦和一种或多种亲水聚合物的水溶液; 并喷雾干燥氯沙坦水溶液和一种或多种亲水聚合物以形成混合物。 无定形氯沙坦和一种或多种亲水聚合物从水溶液中共沉淀。
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公开(公告)号：US20060039968A1
公开(公告)日：2006-02-23
申请号：US10530592
申请日：2003-10-08
IPC分类号： A61K9/20
CPC分类号： A61K31/517 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K9/2866 , A61K31/195 , Y02A50/465
摘要： The present invention is generally directed to methods for preparing stable gabapentin tablets by wet granulation. A wet granulation method for preparing gabapentin tablets includes forming a mixture by dry mixing of a first portion of a binder with the gabapentin, one or more excipients, or a combination of the gabapentin and the one or more excipients; and adding a second portion of the binder to the mixture, wherein the second portion of the binder is in the form of a solution or dispersion.
摘要翻译： 本发明一般涉及通过湿法制粒制备稳定的加巴喷丁片剂的方法。 用于制备加巴喷丁片剂的湿法制粒方法包括通过干燥混合粘合剂的第一部分与加巴喷丁，一种或多种赋形剂或加巴喷丁与一种或多种赋形剂的组合来形成混合物; 以及将粘合剂的第二部分加入到混合物中，其中粘合剂的第二部分是溶液或分散体的形式。
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公开(公告)号：US20070014850A1
公开(公告)日：2007-01-18
申请号：US10523116
申请日：2003-08-01
CPC分类号： A61K9/0095 , A61K9/2009 , A61K31/545
摘要： The present invention relates to dispersible tablets of cephalexin and a process for their preparation.
摘要翻译： 本发明涉及头孢氨苄的分散片剂及其制备方法。
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