公开(公告)号：US07077860B2

公开(公告)日：2006-07-18

申请号：US10877527

申请日：2004-06-24

申请人： John Y. Yan ,  Randy Chan

发明人： John Y. Yan ,  Randy Chan

IPC分类号： A61F2/06

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/92 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L31/10 ,  A61L33/0011 ,  A61L2420/08 ,  Y10S623/921

摘要： An implantable stent is coated with a material that attracts heparin and with which heparin forms a bond. The stent is exposed to a heparin containing solution just prior to implantation or is first implanted and then exposed to heparinized blood. As heparin becomes detached from the stent, the implantation site is exposed to heparin to restore an effective level and thereby prevent thrombosis.

摘要翻译： 可植入支架涂覆有吸引肝素并与肝素形成结合的材料。 支架在植入之前暴露于含有肝素的溶液，或者首先植入，然后暴露于肝素化血液。 随着肝素从支架脱离，植入部位暴露于肝素以恢复有效水平，从而防止血栓形成。

公开(公告)号：US06776792B1

公开(公告)日：2004-08-17

申请号：US08847763

申请日：1997-04-24

申请人： John Y. Yan ,  Randy Chan

发明人： John Y. Yan ,  Randy Chan

IPC分类号： A61F206

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/92 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L31/10 ,  A61L33/0011 ,  A61L2420/08 ,  Y10S623/921

摘要： An implantable stent is coated with a material that attracts heparin and with which heparin forms a bond. The stent is exposed to a heparin containing solution just prior to implantation or is first implanted and then exposed to heparinized blood. As heparin becomes detached from the stent, the implantation site is exposed to heparin to restore an effective level and thereby prevent thrombosis.

摘要翻译： 可植入支架涂覆有吸引肝素并与肝素形成结合的材料。 支架在植入之前暴露于含有肝素的溶液，或者首先植入，然后暴露于肝素化血液。 随着肝素从支架脱离，植入部位暴露于肝素以恢复有效水平，从而防止血栓形成。

公开(公告)号：US06605114B1

公开(公告)日：2003-08-12

申请号：US09430230

申请日：1999-10-29

申请人： John Y. Yan ,  Randy Chan

发明人： John Y. Yan ,  Randy Chan

IPC分类号： A61F206

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/92 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L31/10 ,  A61L33/0011 ,  A61L2420/08 ,  Y10S623/921

摘要： A method for delivering heparin, wherein an implantable stent is coated with a material that attracts heparin and with which heparin forms a bond. The stent is exposed to a heparin containing solution just prior to implantation or is first implanted and then exposed to heparinized blood. As heparin becomes detached from the stent, the implantation site is exposed to heparin to restore an effective level and thereby prevent thrombosis.

摘要翻译： 一种递送肝素的方法，其中可植入支架涂覆有吸引肝素并与肝素形成结合的材料。 支架在植入之前暴露于含有肝素的溶液，或者首先植入，然后暴露于肝素化血液。 随着肝素从支架脱离，植入部位暴露于肝素以恢复有效水平，从而防止血栓形成。

公开(公告)号：US20060178738A1

公开(公告)日：2006-08-10

申请号：US11398826

申请日：2006-04-05

申请人： John Yan ,  Randy Chan

发明人： John Yan ,  Randy Chan

IPC分类号： A61F2/06

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/92 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L31/10 ,  A61L33/0011 ,  A61L2420/08 ,  Y10S623/921

摘要： An implantable stent is coated with a material that attracts heparin and with which heparin forms a bond. The stent is exposed to a heparin containing solution just prior to implantation or is first implanted and then exposed to heparinized blood. As heparin becomes detached from the stent, the implantation site is exposed to heparin to restore an effective level and thereby prevent thrombosis.

摘要翻译： 可植入支架涂覆有吸引肝素并与肝素形成结合的材料。 支架在植入之前暴露于含有肝素的溶液，或者首先植入，然后暴露于肝素化血液。 随着肝素从支架脱离，植入部位暴露于肝素以恢复有效水平，从而防止血栓形成。