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1.发明申请METHOD OF ADMINISTERING AN ACTIVE INGREDIENT USING A CHEWABLE ORAL DOSAGE FROM COMPRISING TEXTURE MASKED PARTICLES 审中-公开使用可纹理口服剂量从包含纹理掩蔽颗粒中施用活性成分的方法公开(公告)号：US20120251623A1
公开(公告)日：2012-10-04
申请号：US13494361
申请日：2012-06-12
CPC分类号： A61K9/5073 , A61K9/0056 , A61K9/2081
摘要： In one aspect, the present invention features a method of administering an active ingredient, said method comprising chewing an oral dosage form comprising a texture masked particle, said texture masked particle comprising a) a core containing an active ingredient; b) a first coating layer comprised of a taste masking agent that substantially covers the core, wherein said taste masking agent is comprised of an insoluble film forming polymer and a non-enteric, water soluble polymer; and c) a second coating layer on the surface of the first coating layer.
摘要翻译： 在一个方面，本发明的特征在于施用活性成分的方法，所述方法包括咀嚼包含纹理掩蔽的颗粒的口服剂型，所述纹理掩蔽的颗粒包含a）含有活性成分的核心; b）由基本上覆盖所述芯的掩味剂组成的第一涂层，其中所述掩味剂由不溶性成膜聚合物和非肠溶性水溶性聚合物组成; 和c）在第一涂层的表面上的第二涂层。
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公开(公告)号：US07223421B2
公开(公告)日：2007-05-29
申请号：US09878034
申请日：2001-06-08
IPC分类号： A61K9/28
CPC分类号： A61K9/0056 , A61K9/2081 , A61K9/5042
摘要： Taste masked particles and chewable tablets made therefrom are disclosed. The taste masked particles comprise a core containing an active ingredient and a polymeric coating covering said core, said coating comprising a mixture of a) an enteric polymer; and b) an insoluble film forming polymer, the surface of said particle being free of active ingredient. The chewable tablets provide immediate release of the active ingredient.
摘要翻译： 公开了由其制成的口味掩模颗粒和咀嚼片。 掩味颗粒包含含有活性成分的芯和覆盖所述芯的聚合物涂层，所述涂层包含a）肠溶性聚合物的混合物; 和b）不溶性成膜聚合物，所述颗粒的表面没有活性成分。 咀嚼片可立即释放活性成分。
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