公开(公告)号：US3975400A

公开(公告)日：1976-08-17

申请号：US334398

申请日：1973-02-21

申请人： Walter Himmele ,  Ernst Hofmann ,  Herwig Hoffmann ,  Reinhold Plass

发明人： Walter Himmele ,  Ernst Hofmann ,  Herwig Hoffmann ,  Reinhold Plass

IPC分类号： C07D207/26 ,  C07D207/267

CPC分类号： C07D207/267

摘要： Method of producing .gamma.-butyrolactams by reacting .gamma.-butyrolactones with ammonia in the presence or absence of water at elevated temperatures and pressures. The reaction is carried out continuously at temperatures ranging from 180.degree. to 340.degree.C whilst maintaining pressures which are at least 10 percent higher than the pressure equal to the sum of the partial pressures of the reactants at the temperature used. .gamma.-Butyrolactams are valuable intermediates, for example in the manufacture of polymers, pharmaceuticals and solvents.

摘要翻译： 在高温和高压下，在存在或不存在水的情况下，使γ-丁内酯与氨反应制备γ-丁内酰胺的方法。 反应在180℃至340℃的温度下连续进行，同时保持比在所用温度下等于反应物分压之和的压力至少高10％的压力。 γ-丁内酰胺是有价值的中间体，例如在聚合物，药物和溶剂的制备中。