公开(公告)号：US20130158482A1

公开(公告)日：2013-06-20

申请号：US13812248

申请日：2011-07-12

申请人： Shawn Davis ,  Donald E. Chickering ,  Remin Haghgooie

发明人： Shawn Davis ,  Donald E. Chickering ,  Remin Haghgooie

IPC分类号： A61M37/00

CPC分类号： A61M37/0015 ,  A61B5/150022 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150282 ,  A61B5/150427 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150511 ,  A61B5/150526 ,  A61B5/150984 ,  A61B5/15113 ,  A61B5/15144 ,  A61B5/157 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  Y10T29/4998

摘要： The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. In another aspect, the present invention is generally directed to arrangements of skin insertion objects such as microneedles and methods of forming and arranging skin insertion objects. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

摘要翻译： 本发明一般涉及用于递送和/或接收物体例如血液的物质，例如来自皮肤和/或皮肤下的受试者的系统和方法。 一方面，本发明一般涉及使用包含流体转运器（例如，一个或多个微针）的装置从皮肤和/或从皮肤下面接收或提取血液的装置和方法 ）和在接收血液之前具有小于大气压的内部压力的储存室。 在一些情况下，该装置可以是独立的，并且在某些情况下，可以将该装置应用于皮肤并被激活以从受试者接收血液。 然后可以处理装置或其一部分，以单独或与外部装置一起确定血液和/或血液内的分析物。 例如，可以从装置接收血液，和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。 在另一方面，本发明一般涉及皮肤插入物体如微针的布置以及形成和布置皮肤插入物体的方法。 本发明的其它方面涉及用于接收血液（或其他体液，例如间质液）的其他装置，涉及这种装置的试剂盒，制造这种装置的方法，使用这种装置的方法等。