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公开(公告)号:US20120295836A1
公开(公告)日:2012-11-22
申请号:US13438970
申请日:2012-04-04
申请人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
发明人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
IPC分类号: A61K38/26 , A61P9/00 , A61P9/12 , A61P19/10 , A61P9/06 , A61P3/10 , A61P3/04 , A61P3/06 , A61P9/10 , A61P9/04
CPC分类号: A61K38/26 , A61K45/06 , C07K14/575 , C07K14/605
摘要: Methods and uses for the treatment and prevention of cardiac and cardiovascular diseases comprising administration of a GLP-1 agonist.
摘要翻译: 用于治疗和预防心脏和心血管疾病的方法和用途,包括施用GLP-1激动剂。
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公开(公告)号:US20090215688A1
公开(公告)日:2009-08-27
申请号:US12133463
申请日:2008-06-05
申请人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
发明人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
CPC分类号: A61K38/26 , A61K45/06 , C07K14/575 , C07K14/605
摘要: Methods and uses for the treatment and prevention of cardiac and cardiovascular diseases comprising administration of a GLP-1 agonist.
摘要翻译: 用于治疗和预防心脏和心血管疾病的方法和用途,包括施用GLP-1激动剂。
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公开(公告)号:US06569832B1
公开(公告)日:2003-05-27
申请号:US09709856
申请日:2000-11-10
申请人: Liselotte Bjerre Knudsen , Carsten Foged Godtfredsen , Jacob Sten Petersen , Richard David Carr , Søren Bregenholt
发明人: Liselotte Bjerre Knudsen , Carsten Foged Godtfredsen , Jacob Sten Petersen , Richard David Carr , Søren Bregenholt
IPC分类号: A16K3800
CPC分类号: A61K38/26
摘要: This invention relates to a method for modulating, inhibiting or decreasing or preventing beta cell degeneration, loss of beta cell function, beta cell dysfunction, and/or death of beta cells, such as necrosis or apoptosis of beta cells in a subject comprising administering a GLP-1 agonist to said subject.
摘要翻译: 本发明涉及一种用于调节,抑制或减少或预防β细胞变性,β细胞功能丧失,β细胞功能障碍和/或β细胞死亡的方法,例如受试者中β细胞的坏死或凋亡,包括施用 GLP-1激动剂。
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公开(公告)号:US07064145B2
公开(公告)日:2006-06-20
申请号:US09790002
申请日:2001-02-21
申请人: Richard David Carr
发明人: Richard David Carr
IPC分类号: A61K31/401
CPC分类号: A61K38/22 , A61K31/00 , A61K31/40 , A61K31/44 , A61K31/4439 , A61K38/2257 , A61K2300/00
摘要: Methods for preventing beta cell degeneration, such as necrosis or apoptosis of beta cells in a subject, comprising administering a DPP-IV inhibitor to a subject in need thereof. The invention furthermore relates to a method for increasing the number and/or the size of beta cells. The invention also relates to a method for delaying the progression of Impaired Glucose Tolerance (IGT) to type 2 diabetes, as well as a method for delaying the progression of non-insulin demanding type 2 diabetes to insulin-demanding type 2 diabetes.
摘要翻译: 用于预防β细胞变性的方法,例如受试者中β细胞的坏死或凋亡,包括向有需要的受试者施用DPP-IV抑制剂。 本发明还涉及增加β细胞的数量和/或尺寸的方法。 本发明还涉及将葡萄糖耐量受损(IGT)延缓到2型糖尿病的进展的方法,以及用于将非胰岛素要求2型糖尿病进展为胰岛素要求2型糖尿病的方法。
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公开(公告)号:US20110230409A1
公开(公告)日:2011-09-22
申请号:US13151618
申请日:2011-06-02
申请人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
发明人: Liselotte Bjerre Knudsen , Bidda Charlotte Rolin , Richard David Carr , Johan Selmer , Jens Larsen , Bodil Elbrond , Lars Bo Nielsen , Christina Christoffersen
CPC分类号: A61K38/26 , A61K45/06 , C07K14/575 , C07K14/605
摘要: Methods and uses for the treatment and prevention of cardiac and cardiovascular diseases comprising administration of a GLP-1 agonist.
摘要翻译: 用于治疗和预防心脏和心血管疾病的方法和用途,包括施用GLP-1激动剂。
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