公开(公告)号：US4887604A

公开(公告)日：1989-12-19

申请号：US194190

申请日：1988-05-16

申请人： Ruth Shefer ,  Robert E. Klinkowstein ,  Richard Petrasso

发明人： Ruth Shefer ,  Robert E. Klinkowstein ,  Richard Petrasso

IPC分类号： A61B6/03 ,  G21K1/10 ,  H05G1/26 ,  H05G1/60

CPC分类号： A61B6/482 ,  A61B6/4035 ,  G21K1/10 ,  H05G1/26 ,  H05G1/60 ,  A61B6/4092

摘要： An energy substraction medical imaging system which is used for imaging a body part impregnated with a radio-opaque dye such as iodine is provided. The system includes an electron beam target having a target surface which, when excited by a high-energy electron beam, generates radiation having strong K.sub..alpha. at energy levels slightly above and slightly below the K-edge energy level of the dye. The target surface is preferably formed of a compound containing lanthanum, such as lanthanum oxide. The target may also be formed of a compound containing a material having a K.sub..alpha. line at an energy level slightly above the dye K-edge and a material with K.sub..alpha. line slightly below the dye K-edge or with separate sections containing such materials which are alternately excited. The target is excited by a high-energy electron beam from a suitable source, the electron beam having sufficient energy to provide a high photon yield at the K.sub..alpha. line energy levels and sufficient power to produce the required photon fluences at such energy lines for the medical imaging application. One of the K.sub..alpha. lines in the radiation output from the excited target is selectively filtered and the output from the filter, both with the K.sub..alpha. line filter and with the line unfiltered, are passed through the body part being imaged to an x-ray detector. The output from the detector in response to the filtered and unfiltered outputs is processed to obtain an image of the body part. Continuum radiation from the target is reduced by filtering the continuum radiation at frequencies above the below the K.sub..alpha. line energy levels of the target compound, by viewing the radiation from the target in the backward direction to the beam, and by having the thickness of the target equal to a fraction of the electron range in the target compound material.

摘要翻译： 提供了用于对浸渍有不透射线的染料如碘的身体部位成像的能量减弱医学成像系统。 该系统包括具有目标表面的电子束目标，当被高能电子束激发时，其产生的能量水平略高于并稍低于染料的K边能级的强Kα辐射。 目标表面优选由含有镧的化合物，例如氧化镧形成。 靶也可以由含有K a线的化合物形成，其能量水平略高于染料K-边缘，并且具有稍低于染料K-边缘的Kα线的材料或含有这些材料的分开的部分 交替激发。 目标被来自合适的源的高能电子束激发，电子束具有足够的能量以在Kα线能量级提供高光子产量，并具有足够的功率以在这样的能量线处产生所需的光子能量， 医学成像应用。 来自激发的靶的辐射输出中的Kα线之一被选择性地滤波，并且来自滤波器的输出（两者都与Kα线滤波器和未被滤波的线路）通过被成像的身体部分被X射线 探测器。 处理来自检测器的响应于滤波和未滤波输出的输出以获得身体部位的图像。 通过在目标化合物的Kα线能级以下的频率处过滤连续体辐射，通过将来自目标的向后方向的辐射观察到束，并通过使靶 目标等于目标化合物中电子范围的一部分。