MICROCANTILEVERS FOR BIOLOGICAL AND CHEMICAL ASSAYS AND METHODS OF MAKING AND USING THEREOF
    1.
    发明申请
    MICROCANTILEVERS FOR BIOLOGICAL AND CHEMICAL ASSAYS AND METHODS OF MAKING AND USING THEREOF 失效
    生物和化学测定微生物及其制备和使用方法

    公开(公告)号:US20070141721A1

    公开(公告)日:2007-06-21

    申请号:US10422776

    申请日:2003-04-25

    IPC分类号: G01N33/543

    CPC分类号: G01N33/54373 B82Y30/00

    摘要: Disclosed herein are microcantilevers having structural shapes that are less sensitive to turbulence and drift effects yet provide greater deflections due to analyte concentration. The structural shapes include a C-shaped microcantilever, an E-shaped microcantilever, an L-shaped microcantilever, a double microcantilever, a slit microcantilever, a tapered microcantilever, and a triangular microcantilever. The microcantilevers may be piezoresistive microcantilevers. Also disclosed are microsensors, microfludic devices, and biochips that comprise the microcantilevers as well as methods of using the microcantilevers to detect analytes in a fluid sample.

    摘要翻译: 本文公开了具有对湍流和漂移效应较不敏感但具有由于分析物浓度引起的更大偏转的结构形状的微悬臂梁。 结构形状包括C形微悬臂梁,E形微悬臂梁,L形微悬臂梁,双微悬臂梁,狭缝微悬臂梁,锥形微悬臂梁和三角形微悬臂梁。 微悬臂梁可以是压阻微型悬臂梁。 还公开了包含微悬臂梁的微传感器,微流体装置和生物芯片以及使用微悬臂梁来检测流体样品中的分析物的方法。

    THREE-DIMENSIONAL MAGNETIC RECORDING
    2.
    发明申请
    THREE-DIMENSIONAL MAGNETIC RECORDING 审中-公开
    三维磁记录

    公开(公告)号:US20100149676A1

    公开(公告)日:2010-06-17

    申请号:US12506042

    申请日:2009-07-20

    IPC分类号: G11B5/127 G11B5/673 G11B5/02

    摘要: A multilayered three-dimensional media having a plurality of magnetic sublayers, each of the magnetic sublayers being separated from one another by a non-magnetic layer. The plurality of magnetic sublayers can be a stack of one or more coupled Co/Pd or Co/Pt layers; a layer of Co—Cr alloys optionally containing TiO2, SiO2, C, Pt, and B; a stack of one or more Co—Cr—Pt/Pt layers; a stack of one or more Co—Cr—Pd/Pd layers; and/or a stack of one or more layers of Fe—Pt, Fe—Pd, Co—Pt, and Co—Pd materials in an L10 phase. The non-magnetic layers are Pd, Pt, Ti, Ta, Cu, Au, Ag, MgO, or/and ITO. In addition, a multilayered three-dimensional recording system is disclosed, which includes a three-dimensional media, the three-dimensional media includes a plurality of magnetic sublayers, wherein each magnetic sublayer is adapted for writing data to; and a recording head having a trailing edge, and wherein the trailing edge has a higher permeability than the recording head.

    摘要翻译: 具有多个磁性子层的多层三维介质,每个磁性子层通过非磁性层彼此分离。 多个磁性子层可以是一个或多个耦合的Co / Pd或Co / Pt层的堆叠; 任选含有TiO 2,SiO 2,C,Pt和B的Co-Cr合金层; 一个或多个Co-Cr-Pt / Pt层的堆叠; 一个或多个Co-Cr-Pd / Pd层的堆叠; 和/或L10相中的一层或多层Fe-Pt,Fe-Pd,Co-Pt和Co-Pd材料。 非磁性层是Pd,Pt,Ti,Ta,Cu,Au,Ag,MgO或/和ITO。 另外,公开了一种多层三维记录系统,其包括三维介质,三维介质包括多个磁性子层,其中每个磁性子层适于写入数据; 以及具有后缘的记录头,并且其中所述后缘具有比所述记录头更高的磁导率。

    Microcantilevers for Biological and Chemical Assays and Methods of Making and Using Thereof
    3.
    发明申请
    Microcantilevers for Biological and Chemical Assays and Methods of Making and Using Thereof 失效
    用于生物和化学测定的微型悬臂梁及其制造和使用方法

    公开(公告)号:US20070287185A1

    公开(公告)日:2007-12-13

    申请号:US11764523

    申请日:2007-06-18

    IPC分类号: G01N33/00 C12M1/00

    CPC分类号: G01N33/54373 B82Y30/00

    摘要: Disclosed herein are microcantilevers having structural shapes that are less sensitive to turbulence and drift effects yet provide greater deflections due to analyte concentration. The structural shapes include a C-shaped microcantilever, an E-shaped microcantilever, an L-shaped microcantilever, a double microcantilever, a slit microcantilever, a tapered microcantilever, and a triangular microcantilever. The microcantilevers may be piezoresistive microcantilevers. Also disclosed are microsensors, microfluidic devices, and biochips that comprise the microcantilevers as well as methods of using the microcantilevers to detect analytes in a fluid sample.

    摘要翻译: 本文公开了具有对湍流和漂移效应较不敏感但具有由于分析物浓度引起的更大偏转的结构形状的微悬臂梁。 结构形状包括C形微悬臂梁,E形微悬臂梁,L形微悬臂梁,双微悬臂梁,狭缝微悬臂梁,锥形微悬臂梁和三角形微悬臂梁。 微悬臂梁可以是压阻微型悬臂梁。 还公开了包含微悬臂梁的微传感器,微流体装置和生物芯片,以及使用微悬臂梁来检测流体样品中的分析物的方法。

    Probes for enhanced magnetic force microscopy resolution
    4.
    发明授权
    Probes for enhanced magnetic force microscopy resolution 有权
    探针增强磁力显微镜分辨率

    公开(公告)号:US08214918B2

    公开(公告)日:2012-07-03

    申请号:US12623329

    申请日:2009-11-20

    IPC分类号: G01Q60/56

    CPC分类号: G01Q60/56

    摘要: Magnetic Force Microscopy (MFM) probe tips that provide enhanced spatial resolution and methods of manufacture are provided. In one aspect, two or more magnetically-decoupled layers may be deposited on an AFM probe in order to create an active magnetic region at about the apex of the probe tip with dimensions less than about 10 nanometers. In another aspect, nanoscale patterning techniques may be employed to fabricate probe tips that possess plateau features. These plateau features may serve as substrates for the deposition of magnetic films having properties similar to magnetic recording media. Machining techniques, such as Focused Ion Beam (FIB) may be further employed to reduce the size of the magnetic materials deposited upon the substrate. Beneficially, because the plateaus of the substrate are substantially flat and of known geometry, and the magnetic properties of magnetic films deposited on flat surfaces are similar to those deposited upon the plateau, the magnetization of the MFM probe tips may be determined to high accuracy. In this manner, fine control over the magnetic properties of MFM probe tips may be achieved, providing enhanced MFM resolution.

    摘要翻译: 提供了提供增强的空间分辨率和制造方法的磁力显微镜(MFM)探针尖端。 在一个方面,可以在AFM探针上沉积两个或更多个磁解耦层,以便在尺寸小于约10纳米的探针尖端的顶点附近形成活性磁区。 在另一方面,可采用纳米尺度图案化技术来制造具有平台特征的探针尖端。 这些高原特征可以用作沉积具有类似于磁记录介质的性质的磁性膜的衬底。 可以进一步采用诸如聚焦离子束(FIB)的加工技术来减小沉积在基底上的磁性材料的尺寸。 有利的是,由于基板的平台基本上是扁平的并且具有已知的几何形状,并且沉积在平坦表面上的磁性膜的磁性能类似于沉积在平台上的磁性膜,所以MFM探针尖端的磁化可以被确定为高精度。 以这种方式,可以实现对MFM探针尖端的磁性能的精细控制,提供增强的MFM分辨率。

    PROBES FOR ENHANCED MAGNETIC FORCE MICROSCOPY RESOLUTION
    5.
    发明申请
    PROBES FOR ENHANCED MAGNETIC FORCE MICROSCOPY RESOLUTION 有权
    探索增强磁力显微镜分辨率

    公开(公告)号:US20100138964A1

    公开(公告)日:2010-06-03

    申请号:US12623329

    申请日:2009-11-20

    IPC分类号: G01Q60/56 G01Q60/54

    CPC分类号: G01Q60/56

    摘要: Magnetic Force Microscopy (MFM) probe tips that provide enhanced spatial resolution and methods of manufacture are provided. In one aspect, two or more magnetically-decoupled layers may be deposited on an AFM probe in order to create an active magnetic region at about the apex of the probe tip with dimensions less than about 10 nanometers. In another aspect, nanoscale patterning techniques may be employed to fabricate probe tips that possess plateau features. These plateau features may serve as substrates for the deposition of magnetic films having properties similar to magnetic recording media. Machining techniques, such as Focused Ion Beam (FIB) may be further employed to reduce the size of the magnetic materials deposited upon the substrate. Beneficially, because the plateaus of the substrate are substantially flat and of known geometry, and the magnetic properties of magnetic films deposited on flat surfaces are similar to those deposited upon the plateau, the magnetization of the MFM probe tips may be determined to high accuracy. In this manner, fine control over the magnetic properties of MFM probe tips may be achieved, providing enhanced MFM resolution.

    摘要翻译: 提供了提供增强的空间分辨率和制造方法的磁力显微镜(MFM)探针尖端。 在一个方面,可以在AFM探针上沉积两个或更多个磁解耦层,以便在尺寸小于约10纳米的探针尖端的顶点附近形成活性磁区。 在另一方面,可采用纳米尺度图案化技术来制造具有平台特征的探针尖端。 这些高原特征可以用作沉积具有类似于磁记录介质的性质的磁性膜的衬底。 可以进一步采用加工技术,例如聚焦离子束(FIB)来减小沉积在基底上的磁性材料的尺寸。 有利的是,由于基板的平台基本上是扁平的并且具有已知的几何形状,并且沉积在平坦表面上的磁性膜的磁性能类似于沉积在平台上的磁性膜,所以MFM探针尖端的磁化可以被确定为高精度。 以这种方式,可以实现对MFM探针尖端的磁性能的精细控制,提供增强的MFM分辨率。