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    Pharmaceutical formulation comprising lanthanum compounds
    1.
    发明申请
    Pharmaceutical formulation comprising lanthanum compounds 有权
    包含镧化合物的药物制剂

    公开(公告)号：US20050079135A1

    公开(公告)日：2005-04-14

    申请号：US10926330

    申请日：2004-08-26

    申请人： Robert Haslam ,  Laura Trespidi ,  Josephine Ferdinando

    发明人： Robert Haslam ,  Laura Trespidi ,  Josephine Ferdinando

    IPC分类号： A61J3/10 ,  A61K9/00 ,  A61K9/20 ,  A61K33/24 ,  A61P13/12 ,  A61K33/00

    CPC分类号： A61K9/0056 ,  A61J3/10 ,  A61K9/2018 ,  A61K33/24

    摘要： This invention relates to a chewable lanthanum formulation comprising a pharmaceutically effective amount of a lanthanum compound; and at least one chewable pharmaceutically acceptable excipient. This invention also relates to a pharmaceutical formulation in a tablet or in a powder comprising a pharmaceutically effective amount of a lanthanum compound produced by a process which comprises the steps of: a) powder blending the lanthanum compound and at least one pharmaceutically acceptable excipient in a mixer to form a mixture; or b) powder blending the lanthanum compound and excipients, compressing the resulting combination into a slug material or roller compacting the resulting combination into a strand material, and milling the prepared material into a free flowing mixture; and c)compressing the resulting mixture into a tablet or filing up the resulting mixture in a appropriate container.

    摘要翻译： 本发明涉及含有药物有效量的镧化合物的咀嚼镧制剂; 和至少一种可咀嚼的药学上可接受的赋形剂。 本发明还涉及片剂或粉末中的药物制剂，其包含药学有效量的通过包括以下步骤的方法制备的镧化合物：a）将镧化合物和至少一种药学上可接受的赋形剂在 混合器形成混合物; 或b）将镧化合物和赋形剂混合的粉末，将所得组合物压缩成块状材料或辊，将所得组合压实成股线材料，并将制备的材料研磨成自由流动的混合物; 和c）将所得混合物压制成片剂或将所得混合物填充在合适的容器中。