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公开(公告)号：US4761483A
公开(公告)日：1988-08-02
申请号：US748890
申请日：1985-06-26
申请人： Kevin R. Lawson , Roger M. Upton
发明人： Kevin R. Lawson , Roger M. Upton
IPC分类号： C07D233/60 , A61K31/415 , A61K38/00 , A61P1/02 , A61P31/04 , C07D233/54 , C07D233/64 , C07D521/00 , C07K5/068 , C07K5/078
CPC分类号： C07D233/64 , C07D231/12 , C07D233/56 , C07D249/08 , C07K5/06086 , C07K5/06139 , A61K38/00
摘要： The present invention relates to a class of novel chloro-substituted ketone imidazole derivatives. The invention further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as anti-anaerobic agents.
摘要翻译： 本发明涉及一类新的氯代酮咪唑衍生物。 本发明还涉及含有这些化合物的药物组合物以及这种化合物和组合物作为抗厌氧剂的用途。
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2.发明授权
公开(公告)号：US4761414A
公开(公告)日：1988-08-02
申请号：US897908
申请日：1986-08-19
IPC分类号： A61K31/495 , A61P31/04 , A61P33/00 , C07D471/14 , C07D471/20 , A61K31/505 , C07D239/70
CPC分类号： C07D471/14
摘要： This disclosure relates to a compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 are independently selected from the class consisting of hydrogen, halo, C.sub.1 -C.sub.6 alkyl, and C.sub.1 -C.sub.6 alkoxy;R.sup.3 and R.sup.4 are independently hydrogen or C.sub.1 -C.sub.6 alkyl or R.sup.3 and R.sup.4 together may be a ##STR2## group wherein n is an integer of from 0 to 4; and X, Y and Z are independently--CH-- or --N.dbd. provided that one and only one of X, Y or Z must be --N.dbd..The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as anti-anaerobic agents.
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公开(公告)号：US4758565A
公开(公告)日：1988-07-19
申请号：US897461
申请日：1986-08-18
IPC分类号： A61K31/505 , A61P31/04 , C07D487/04
CPC分类号： C07D487/04
摘要： This disclosure relates to a novel class of substituted quinoxaline derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as anti-anaerobic agents.
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