公开(公告)号：US4717668A

公开(公告)日：1988-01-05

申请号：US940889

申请日：1986-12-12

申请人： Michael R. Keilman ,  Ronald P. Symbol

发明人： Michael R. Keilman ,  Ronald P. Symbol

IPC分类号： C12M3/04 ,  C12M1/24

CPC分类号： C12M27/12 ,  C12M23/08 ,  C12M23/26 ,  C12M37/00 ,  Y10S215/03

摘要： A plastic roller bottle is provided for suspension cultures for bacteriology or other cell growth or maintenance. The roller bottle comprises a closed bottle defining a longitudinal axis and having flexible plastic walls. Aseptically sealable means for access into the closed body are provided as well. A plurality of spaced reinforcement rings are defined in the flexible plastic walls about the longitudinal axis, to cause the body to normally retain a predetermined, generally cylindrical shape. The flexible plastic walls, apart from the rings, are made of a plastic formulation, and are of a thickness such that the oxygen and carbon dioxide diffusion which takes place through said walls is sufficient to support desired biochemical culturing processes taking place within the roller bottle without venting.

摘要翻译： 为悬浮培养物提供塑料滚瓶用于细菌学或其他细胞生长或维持。 辊瓶包括限定纵向轴线并具有柔性塑料壁的封闭瓶。 还提供用于进入封闭体的无菌密封装置。 在柔性塑料壁中围绕纵向轴线限定多个间隔开的加强环，以使得主体通常保持预定的大致圆柱形形状。 除了环之外，柔性塑料壁由塑料制剂制成，并且具有使得通过所述壁发生的氧气和二氧化碳扩散足以支撑在辊瓶内发生的期望的生化培养过程的厚度 没有通风。