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公开(公告)号:US20110300154A1
公开(公告)日:2011-12-08
申请号:US12674191
申请日:2008-08-21
申请人: Dale T. Umetsu , Muriel Pichavant , Rosemarie Helena DeKruyff-Umetsu , Everett Hurteau Meyer , Stephanie Ann Shore
发明人: Dale T. Umetsu , Muriel Pichavant , Rosemarie Helena DeKruyff-Umetsu , Everett Hurteau Meyer , Stephanie Ann Shore
IPC分类号: A61K39/395 , A61K31/7088 , A61P11/06 , A61K31/7028 , A61P37/06 , A61K38/17 , A61K31/713
CPC分类号: A61K38/1793 , A61K31/00 , C12N15/1136 , C12N2310/11 , C12N2310/14 , A61K2300/00
摘要: The invention provides strategies for treating and preventing airway hyperreactivity and non-allergic asthma comprising antagonizing IL-17 activity and/or production by iNKT cells. Provided herein is a method of diagnosing non-allergic asthma and airway hyperreactivity comprising neutrophils quantification in sputum.
摘要翻译: 本发明提供治疗和预防气道高反应性和非过敏性哮喘的策略,其包括拮抗IL-17活性和/或由iNKT细胞产生。 本文提供了一种诊断非过敏性哮喘和气道高反应性的方法,其包括痰中的嗜中性粒细胞定量。