公开(公告)号：US06331402B1

公开(公告)日：2001-12-18

申请号：US09344587

申请日：1999-06-25

申请人： Sabine Nussbaum ,  Ellen Moessner ,  Helmut Lenz ,  Gerald Praast

发明人： Sabine Nussbaum ,  Ellen Moessner ,  Helmut Lenz ,  Gerald Praast

IPC分类号： C12Q100

CPC分类号： G01N33/5306

摘要： The invention concerns an immunological process for the detection of an analyte in a sample, in particular of tumor markers wherein for the reduction of interference substances containing a peptide sequence derived from the framework regions of the variable domain of the antibodies to be detected or the antibodies used for immune therapy or scintigraphy are added to the test preparation. Furthermore, the invention concerns the use of such substances for the reduction of interference of immunoassays, a suppressive agent and a process for the reduction of interference of immunoassays by the substances mentioned.

摘要翻译： 本发明涉及用于检测样品中特别是肿瘤标志物的分析物的免疫学过程，其中为了减少含有源自待检测抗体的可变结构域的框架区的肽序列或抗体 用于免疫治疗或闪烁扫描法加入到试验制剂中。 此外，本发明涉及这些物质用于减少免疫测定的干扰，抑制剂以及通过所述物质减少免疫测定的干扰的方法。