公开(公告)号：US5705039A

公开(公告)日：1998-01-06

申请号：US542612

申请日：1995-10-13

申请人： Sam F. Clarke ,  Venkataraman Ramachandran ,  J. Steve Staton ,  Paul L. Wiggins

发明人： Sam F. Clarke ,  Venkataraman Ramachandran ,  J. Steve Staton ,  Paul L. Wiggins

IPC分类号： B01D3/14 ,  C07C37/74 ,  B01D3/00 ,  C07C37/68

CPC分类号： B01D3/146 ,  C07C37/685 ,  C07C37/74 ,  Y10S203/07 ,  Y10S203/09

摘要： Impure 2,6-diisopropylphenol (DIP) is purified by use of a distillation process in which a single distillation column is used. The process comprises: (a) subjecting the impure DIP to a first continuous distillation in the column in an inert environment to distill off lower boiling components and produce first column bottoms enriched in DIP; (b) collecting, cooling and storing the first column bottoms while continuously maintaining them in an inert environment; (c) discontinuing the first continuous distillation; (d) subjecting the first column bottoms to a second continuous distillation in an inert environment in the same column to produce a second overhead distillate composed of purified DIP. The process avoids the formation in the distilling mixtures of dose boiling impurities due to seepage of air through standard pipe flanges and fittings and consequent oxidation reactions which occur under the conditions needed for batch distillations conducted in typical industrial distillation facilities. These impurities include 2,6-diisopropylbenzoquinone, 2-isopropyl-6-isopropenylphenol, 2,6-diisopropenylphenol and 2,2-dimethyl-4-isopropyl-1,3-benzodioxole. The capital investment needed for a conventional continuous distillation facility is also avoided.

摘要翻译： 不纯的2,6-二异丙基苯酚（DIP）通过使用其中使用单个蒸馏塔的蒸馏方法纯化。 该方法包括：（a）使惰性DIP在惰性环境中在柱中进行第一次连续蒸馏以蒸馏掉低沸点组分并产生富含DIP的第一塔底物; （b）收集，冷却和储存第一塔底，同时将其保持在惰性环境中; （c）停止第一次连续蒸馏; （d）在同一塔的惰性环境中对第一塔底部进行第二次连续蒸馏以产生由纯化的DIP组成的第二塔顶馏出物。 该过程避免了在典型工业蒸馏设备中进行的批次蒸馏所需的条件下，由于通过标准管道法兰和配件的空气渗漏导致的沸腾杂质的蒸馏混合物中的形成以及随之而来的氧化反应。 这些杂质包括2,6-二异丙基苯醌，2-异丙基-6-异丙烯基苯酚，2,6-二异丙烯基苯酚和2,2-二甲基-4-异丙基-1,3-苯并间二氧杂环戊烯。 也避免了常规连续蒸馏设备所需的投资。