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公开(公告)号:US20110314915A1
公开(公告)日:2011-12-29
申请号:US13254779
申请日:2010-03-05
IPC分类号: G01N29/04
CPC分类号: G01M5/0066 , G01M5/0033 , G01M5/0091 , G01M7/025 , G01M7/06 , G01N29/043 , G01N29/045 , G01N29/2418 , G01N2291/0231 , G01N2291/0258
摘要: Methods and apparatus for exciting a structure and determining its structural integrity. In particular, methods of nonlinear analysis are used to compare first and second response datasets, each dataset resulting from a different excitation amplitude that the other dataset.
摘要翻译: 用于激发结构并确定其结构完整性的方法和装置。 特别地,非线性分析方法用于比较第一和第二响应数据集,每个数据集由另一数据集的不同激励幅度产生。
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公开(公告)号:US20100008917A1
公开(公告)日:2010-01-14
申请号:US12438909
申请日:2007-08-27
申请人: Nancy Hosken , Kelly Byrnes-Blake , Ty Brender , Monica J. Huber , Margaret D. Moore , Shirley Rene , Mark W. Rixon , Sara Underwood
发明人: Nancy Hosken , Kelly Byrnes-Blake , Ty Brender , Monica J. Huber , Margaret D. Moore , Shirley Rene , Mark W. Rixon , Sara Underwood
IPC分类号: A61K39/395
CPC分类号: A61K9/0019 , A61K38/1793 , A61K2039/505 , C07K16/2866 , C07K2319/30 , A61K2300/00
摘要: Methods of treating aplastic anemia in a patient and of increasing blood cell production in a patient having aplastic anemia are disclosed. The methods comprise administering to the patient a therapeutically effective amount of an IL-27 antagonist in combination with a pharmaceutically acceptable vehicle. IL-27 antagonists include soluble IL-27RA proteins and antagonists that comprise an antigen-binding site of an antibody.
摘要翻译: 公开了治疗再生障碍性贫血患者的再生障碍性贫血的治疗方法和增加血细胞生成的方法。 所述方法包括向患者施用治疗有效量的IL-27拮抗剂与药学上可接受的载体。 IL-27拮抗剂包括可溶性IL-27RA蛋白和包含抗体的抗原结合位点的拮抗剂。
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公开(公告)号:US20100092465A1
公开(公告)日:2010-04-15
申请号:US12438903
申请日:2007-08-27
申请人: Nancy Hosken , Kelly Byrnes-Blake , Ty Brender , Monica Huber , Margaret Moore , Shirley Rene , Mark Rixon , Sara Underwood , Kimberly Waggie
发明人: Nancy Hosken , Kelly Byrnes-Blake , Ty Brender , Monica Huber , Margaret Moore , Shirley Rene , Mark Rixon , Sara Underwood , Kimberly Waggie
IPC分类号: A61K39/395 , A61P37/06
CPC分类号: C07K16/2866 , A61K38/1793 , A61K2039/505 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: Methods for treating graft-versus-host disease, methods for reducing symptoms of graft-versus-host disease, and methods of reducing the severity of graft-versus-host disease in a patient are disclosed. The methods comprise administering to the patient a therapeutically effective amount of an IL-27 antagonist in combination with a pharmaceutically acceptable vehicle. IL-27 antagonists include soluble IL-27RA proteins and antagonists that comprise an antigen-binding site of an antibody.
摘要翻译: 公开了用于治疗移植物抗宿主病的方法,减少移植物抗宿主病的症状的方法以及降低患者中移植物抗宿主病的严重性的方法。 所述方法包括向患者施用治疗有效量的IL-27拮抗剂与药学上可接受的载体的组合。 IL-27拮抗剂包括可溶性IL-27RA蛋白和包含抗体的抗原结合位点的拮抗剂。
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公开(公告)号:US08656779B2
公开(公告)日:2014-02-25
申请号:US13254779
申请日:2010-03-05
IPC分类号: G01N29/04
CPC分类号: G01M5/0066 , G01M5/0033 , G01M5/0091 , G01M7/025 , G01M7/06 , G01N29/043 , G01N29/045 , G01N29/2418 , G01N2291/0231 , G01N2291/0258
摘要: Methods and apparatus for exciting a structure and determining its structural integrity. In particular, methods of nonlinear analysis are used to compare first and second response datasets, each dataset resulting from a different excitation amplitude that the other dataset.
摘要翻译: 用于激发结构并确定其结构完整性的方法和装置。 特别地,非线性分析方法用于比较第一和第二响应数据集,每个数据集由另一数据集的不同激励幅度产生。
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