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公开(公告)号:US20070123535A1
公开(公告)日:2007-05-31
申请号:US11605729
申请日:2006-11-29
申请人: Robert Greenhouse , Saul Jamie-Figueroa , Stephen Lynch , Lubica Raptova , Karin Stein , Robert Weikert
发明人: Robert Greenhouse , Saul Jamie-Figueroa , Stephen Lynch , Lubica Raptova , Karin Stein , Robert Weikert
IPC分类号: A61K31/519 , A61K31/506 , A61K31/4745 , C07D487/02 , C07D471/02
CPC分类号: C07D471/04 , C07D487/04 , C07D487/14
摘要: The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
摘要翻译: 本发明提供下式的化合物或其药学上可接受的盐,溶剂合物或前药,其中p,Ar,R 1,R 2,R 3, R SUP,R,B,R,C,R,D, / SUP>。 还提供药物组合物,使用方法和制备化合物的方法。