专利检索 ap:"Seattle Children's Hospital (dba Seattle Children'a Research Institute)" 第 1 页

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发明申请
SODIUM FLUORESCEIN AS A REVERSAL AGENT FOR AN ANTI-FLUORESCEIN CAR T CELLS AND FLUORESCEIN-PHOSPHOLIPID-ETHERS OR PROFLUORESCEIN-PHOSPHOLIPID-ETHERS 有权

公开(公告)号：US20220125841A1

公开(公告)日：2022-04-28

申请号：US17438231

申请日：2020-03-11

申请人： Seattle Children's Hospital (dba Seattle Children'a Research Institute)

发明人： Michael C. Jensen , James Matthaei

IPC分类号： A61K35/17 , A61P35/00 , C07K14/725

摘要： Some embodiments of the methods and compositions provided herein relate to modulating signaling of anti-hapten CAR T cells, such as anti-fluorescein CAR T cells, by the use or administration of an unconjugated hapten, such as unconjugated fluorescein or a salt or derivative thereof.