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公开(公告)号：US20200345751A1
公开(公告)日：2020-11-05
申请号：US16932382
申请日：2020-07-17
发明人： Henk SWART
IPC分类号： A61K31/565 , A61K47/54 , A61K9/00 , A61K9/20 , A61K31/566 , C08B37/16 , A61K47/69 , A61K9/08 , A61K47/40
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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公开(公告)号：US20170266203A1
公开(公告)日：2017-09-21
申请号：US15615295
申请日：2017-06-06
发明人： Henk Swart
IPC分类号： A61K31/565 , A61K31/566 , A61K47/40 , A61K9/00 , A61K9/20 , B82Y5/00 , C08B37/16
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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公开(公告)号：US20180071309A9
公开(公告)日：2018-03-15
申请号：US15615295
申请日：2017-06-06
发明人： Henk Swart
IPC分类号： A61K31/565 , C08B37/16 , B82Y5/00 , A61K47/40 , A61K31/566 , A61K9/20 , A61K9/00
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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公开(公告)号：US11452729B2
公开(公告)日：2022-09-27
申请号：US16932382
申请日：2020-07-17
发明人： Henk Swart
IPC分类号： A61K31/565 , A61K47/69 , A61K9/08 , A61K47/54 , A61K9/00 , A61K9/20 , A61K31/566 , C08B37/16 , A61K47/40 , B82Y5/00
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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公开(公告)号：US20210315905A9
公开(公告)日：2021-10-14
申请号：US16932382
申请日：2020-07-17
发明人： Henk SWART
IPC分类号： A61K31/565 , A61K47/54 , A61K9/00 , A61K9/20 , A61K31/566 , C08B37/16 , A61K47/69 , A61K9/08 , A61K47/40
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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公开(公告)号：US10758547B2
公开(公告)日：2020-09-01
申请号：US15615295
申请日：2017-06-06
发明人： Henk Swart
IPC分类号： A61K31/565 , A61K9/08 , A61K47/40 , A61K47/54 , A61K9/00 , A61K9/20 , A61K31/566 , C08B37/16 , A61K47/69 , B82Y5/00
摘要： Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus erythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
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