公开(公告)号：US3962443A

公开(公告)日：1976-06-08

申请号：US551923

申请日：1975-02-21

申请人： Shinsaku Minami ,  Jun-ichi Matsumoto ,  Kazuyo Kawaguchi ,  Shinsaku Mishio ,  Masanao Shimizu ,  Yoshiyuki Takase ,  Shinichi Nakamura

发明人： Shinsaku Minami ,  Jun-ichi Matsumoto ,  Kazuyo Kawaguchi ,  Shinsaku Mishio ,  Masanao Shimizu ,  Yoshiyuki Takase ,  Shinichi Nakamura

IPC分类号： A61K31/505

摘要： This invention provides compounds of the following formula ##SPC1##Wherein R.sub.1 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a hydroxyalkyl group having 2 to 4 carbon atoms, a benzyl group, a benzyl group subsituted by methoxy, a phenyl group, a propargyl group or an acyl group; R.sub.2 is hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkyl group having 2 to 4 carbon atoms substituted by hydroxy or halogen, a vinyl group, an allyl group, or a benzyl group R.sub.3 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms;And salts thereof, and processes for preparing them. Some of the compounds have antibacterial activities.

摘要翻译： 本发明提供下式的化合物，其中R 1是氢原子，具有1至4个碳原子的烷基，具有2至4个碳原子的羟基烷基，苄基，被甲氧基取代的苄基，苯基， 炔丙基或酰基; R2为氢原子，碳原子数为1〜4的烷基，被羟基或卤素取代的碳原子数为2〜4的烷基，乙烯基，烯丙基或苄基R 3为氢原子或烷基 具有1至6个碳原子的基团; 及其制备方法及其制备方法。 一些化合物具有抗菌活性。